Accompanying HIV-positive adolescents through the transition into adult care: a feasibility study

项目摘要/摘要 过渡到成人艾滋病毒护理通常伴随着药物依从性、滞留、艾滋病毒病毒载量的减少 抑制和CD4细胞计数；然而，人们对哪些干预措施可能在以下方面最有效知之甚少 支持正在经历这一关爱过渡的青少年。我们将进行以社区为基础的 由社区卫生工作者提供的旨在改善健康的伴奏干预 秘鲁城市青少年过渡到成人护理的结果。我们将(1)进行干预试点 为了确定旨在改善病毒载量滞留的伴随干预的可行性 在不同的艾滋病毒携带者青少年队列中进行抑制(即“成功过渡”)；(2)初步研究 与未来干预试验相关的程序；以及(3)进行回顾图表审查，以收集数据以 为将来的干预试验通知招募和样本量计算。

PROJECT SUMMARY/ABSTRACT The transition to adult HIV care is often accompanied by reduced medication adherence, retention, HIV viral load suppression and CD4 cell counts; however, little is known about which interventions might be most effective in supporting adolescents undergoing this care transition. We will conduct a feasibility study for a community-based accompaniment intervention, delivered by community health workers, that is designed to improve health outcomes among adolescents transitioning to adult care in urban Peru. We will (1) conduct an intervention pilot to determine the feasibility of an accompaniment intervention designed to improved retention with viral load suppression (i.e., “successful transition”) among a diverse cohort of adolescents living with HIV; (2) pilot study procedures relevant to a future intervention trial; and (3) conduct a retrospective chart review to collect data to inform recruitment and sample size calculations for a future intervention trial.