Magnetic Seizure Therapy:The Neural Correlates and Neurocognitive Outcomes of a Novel Therapeutic Approach to Depression

抑郁症是一个重要的临床问题，ECT是最有效的治疗方法。然而，电痉挛疗法有认知方面的副作用，这限制了它的适用性和患者的接受度。开发一种新的治疗方法，具有相似的疗效，但最大限度地减少这些副作用，将具有很大的临床价值。一种有希望的可能性是磁发作疗法（MST）。本项目将研究MST在抑郁症中的神经学结果，重点是认知结果。

Depression is a substantial clinical problem for which ECT is the most efficacious treatment. However, ECT has cognitive side-effects which limit its applicability and acceptance by patients. The development of a new treatment with similar efficacy but which minimizes these side effects would have great clinical value. One promising possibility is magnetic seizure therapy (MST). This project will investigate the neurological outcomes of MST in depression, focusing on the cognitive outcomes.