Vermont Genetics Network - Vermont INBRE

项目摘要 佛蒙特州遗传学网络(VGN)的使命是在佛蒙特州建立生物医学研究基础设施。 我们的重点是广义上的人类健康和行为。其目标是建立和维持一种研究文化 在佛蒙特州，通过促进教职员工的研究能力和教育 我们学士学位合作院校的本科生。 我们在主要机构佛蒙特州大学(UVM)创建了最先进的设施，为 网络；在VGN文凭合作机构(BPI)促进教职员工和学生的研究，并获得研究奖项 和指导；并为BPI和其他学院提供实习经验和课程模块，供学生 具有研究方案的实践经验，并使用VGN的设施。评估显示，VGN资助的教职员工 BPI和UVM正在发布并变得具有竞争力。我们在INBRE 3头三年半的努力取得了以下成果 114份出版物(公众宣传局教职员工=31份；生物信息学=21份；蛋白质组学=50份；微阵列=12份)，67份校外补助金(过去 和目前在INBRE资助的BPI教职员工=21人；生物信息学=8人；蛋白质组学=38人)资助或促进VGN教职员工 由VGN和146名学生在STEM领域实习，其中89%的学生在STEM领域工作或追求 在STEM领域的研究生工作。我们努力促进研究文化，并提供设施来促进教师的发展。 研究和学生培训。 INBRE 4中的四个新的具体目标是在成功的基础上为VGN带来创新：1.加强对教职员工的建议 为资助/接受出版物的资助和论文提供便利；2.建立跨学科的教员专题小组 鼓励学者合作，提高研究询问的质量；3.提升教育体验 继续让本科生多元化；以及4.继续透过我们的 生物信息学核心、蛋白质组学核心、核心市场，以及与其他INBRE和UVM Cobres的合作。这个 专业发展和教育核心将实施目标1、2和3。生物信息学核心将实施 目标4(以及目标1和3)，为VGN设施提供关键数据分析支持；协助 网络学院，用于研究和将研究融入课堂；以及支持网络的网络基础设施 通信和数据管理。蛋白质组学基金将于#年实施目标4(以及目标1和3)。 进行蛋白质组分析(我们的设施是佛蒙特州唯一一家提供全方位服务的机构，促进研究结果的发布， 为学生提供教育机会。行政核心将提供后勤、财务、 合规监督和外部评估，以确保VGN对不断变化的需求和不断发展的优势敏感 网络机构。行政核心安排指导和本科生实习生计划以 通过PDE Core增加生物医学员工队伍的规模和多样性。我们对人类健康和行为的关注 与我们之前对遗传学的关注相比，BPI允许更多的参与。VGN有强有力的支持和承诺 来自所有网络机构以及区域INBRE和Cobres之间的合作。

Project Summary The Mission of the Vermont Genetics Network (VGN) is to build the biomedical research infrastructure in Vermont. Our focus is on human health and behavior as broadly defined. The goal is to build and sustain a culture of research throughout the State of Vermont by facilitating the research capacity of faculty members and the education of undergraduates at our baccalaureate partner institutions. We have created state-of-the-art facilities at the University of Vermont (UVM), the lead institution, to serve the network; promoted faculty and student research at VGN Baccalaureate Partner Institutions (BPIs) with research awards and mentoring; and provided BPIs and other colleges with internship experiences and class modules for students to have hands-on experience with research protocols and use VGN’s facilities. Assessments show that VGN-funded faculty at BPIs and UVM are publishing and becoming competitive. Our efforts in the first 3 ½ years of INBRE 3 have resulted in 114 publications (BPI faculty = 31; Bioinformatics = 21; Proteomics = 50; Microarray = 12), 67 extramural grants (past and current BPI faculty funded in INBRE 3 = 21; Bioinformatics = 8; Proteomics = 38) funded to VGN faculty or facilitated by VGN, and 146 students serving as interns in the STEM fields with 89% of those tracked working in or pursuing graduate work in a STEM field. Our efforts promote a culture of research and provide the facilities to promote faculty research and student training. Four new specific aims in INBRE 4 build upon successes and bring innovation to VGN: 1. Enhance advising of faculty to facilitate grants and articles funded/accepted for publications; 2. Build interdisciplinary thematic groups of faculty scholars to encourage collaboration and enhance the quality of research inquiries; 3. Enhance educational experiences and continue diversification of undergraduates; and 4. Continue to enhance sharing of research resources through our Bioinformatics Core, Proteomics Core, Core Marketplace, and collaboration with other INBREs and UVM COBREs. The Professional Development and Education Core will implement Aims 1, 2, and 3. The Bioinformatics Core will implement Aim 4 (as well as Aims 1 and 3) by providing critical data analysis support for the VGN facilities; giving assistance to network faculty for research and incorporation of research into classes; and supporting cyber infrastructure for network communication and data management. The Proteomics Facility will implement Aim 4 (as well as Aims 1 and 3) by conducting proteomic analyses (our Facility is the only full service one in Vermont, facilitating publication of findings, and providing educational opportunities for students. The Administrative Core will provide logistical, financial, compliance oversight, and external evaluation to ensure that VGN is sensitive to changing needs and evolving strengths of the network institutions. The Administrative Core arranges mentoring and undergraduate intern programs to increase the biomedical workforce size and diversity through the PDE Core. Our focus on Human Health and Behavior allows for greater participation at BPIs than our earlier focus on genetics. VGN has strong support and commitments from all network institutions and collaborations among regional INBREs and COBREs.