Administrative Core

项目摘要 摘要：行政核心的总体目标是整合和集中所有 确保科布雷宿主-病原体相互作用中心取得成功所需的资源。这个核心 将支持专注于确定免疫调节的潜在机制的研究人员 对各种感染进行宿主，并找出针对这些毁灭性疾病的可能治疗方法。在上下文中 在目前资金紧张的环境下，成功取决于许多因素，包括优秀的导师， 获得足够的研究空间、现代设备和现有技术，不受 管理负担，以及在这个充满活力的研究人员社区内促进的协作 在各种传染病模型中研究宿主-病原体相互作用的共同兴趣。因此，我们 认为人类的共同努力对于建立我们的研究企业是必不可少的。因此， 管理核心将支持我们集团活动的许多基本方面，包括(1)实施 全面但个性化的指导计划；(2)提供有组织的机会，以建立和 促进小组内富有成效的科学互动；(3)提高小组的国家形象和 建立2个新的核心设施；(4)培训调查人员如何最好地利用先进的 可供他们使用的技术；(5)支持我们的访问演讲者系列研讨会；(6)支持特定的 与传染病相关的医学与健康科学学院图书馆的采购；(7)组织我们的 年度研讨会/讲习班；(8)通过其他北方国家之间的年度会议促进合作 达科他州科布雷和INBRE赠款资助的团体以及各自团体中的个人之间；以及 (9)支持我们的内部咨询和指导委员会成员参与的导师计划 我们的外部咨询委员会发挥着积极的作用。作为我们导师计划的一部分，我们将每月 会议的重点是科学，科学合作，以教师为导向的生存技能，拨款申请，以及 获得资金以建立个人和团队的成功。我们相信，我们的初级教员将作为一个 这种承诺互动的结果，将这个研究小组建设成一个具有更高国际知名度的研究小组。

Project Summary Summary: The overall purpose of the Administrative Core is to consolidate and centralize all of the necessary resources to ensure the success of the COBRE Center on Host-pathogen Interactions. This core will support investigators focused on determining the mechanisms underlying immune modulations in the host upon various infections and to identify possible treatments for these devastating illnesses. In the context of the current tight funding environment, success depends on many factors including excellent mentorship, access to adequate research space, modern equipment, and current technology, freedom from administrative burdens, along with facilitated collaboration within this vibrant community of researchers with a common interest in studying the host-pathogen interactions in various infectious disease models. Thus, we view a concerted human effort as being essential to build our research enterprise. Accordingly, the Administrative Core will support many essential aspects of our group's activities including (1) implementing a comprehensive, but individualized mentoring program; (2) providing structured opportunities to establish and facilitate productive scientific interactions within the group; (3) raising the national profile of the group and establishing 2 new core facilties; (4) training investigators in how best to take advantage of the advanced technologies available to them; (5) supporting our visiting speaker seminar series; (6) supporting specific infectious disease-related School of Medicine and Health Sciences library acquisitions; (7) organizing our annual symposium/workshop; (8) fostering collaborations through annual meetings between the other North Dakota COBRE and INBRE grant supported groups and between individuals in the respective groups; and (9) supporting mentorship programs for which members of our Internal Advisory and Mentoring Committee and our External Advisory Board play active roles. As part of our mentorship program we will have monthly meetings focusing on science, scientific collaborations, faculty-orientated survival skills, grant writing, and obtaining funding to build individual and group success. We are confident that our junior faculty will, as a result of such committed interactions, build this research group to one of increased international prominence.