Bioinformatics Core

生物信息学核心项目总结 缅因州IDEA生物医学研究卓越网络(ME-INBRE)生物信息学核心将支持 通过提供生物信息学方面的基本咨询和培训，开展比较功能基因组学研究。 生物医学研究越来越多地利用高通量技术，核心将提供 管理、分析和解释大型数据集所需的专业知识。专家核心员工将 建议和/或与ME-INBRE研究人员合作，在实验中应用最佳实践 基因组数据分析的设计、数据管理和最先进的工作流程，特别关注 严密性和可重复性。核心人员还将为ME-INBRE项目负责人提供访问和专业知识的机会 在使用跨越本地、区域和云计算资源的适当网络基础设施方面。这个 生物信息核心公司将通过东北地区利用区域合作和网络基础设施 ME-INBRE与其他四个想法国家共同创建的网络基础设施联盟(NECC) 区域网络基础设施和开展协作性网络研究。穿越东北 生物信息学合作(NEBC)，核心将与位于特拉华州的INBRE生物信息学核心员工合作， 新罕布夏州、罗德岛州和佛蒙特州的咨询项目，以支持缅因州的教师和合作 向教职员工和学生提供生物信息学培训。区域网络基础设施将用于 密集的计算和集中的数据存储、共享和备份。核心将维护和构建 根据其建立的生物信息学培训课程和研讨会，面向从 本科生级别的教员调查人员，并将继续支持缅因州大学的专业人员 生物信息学硕士项目和生物信息学学者项目，它们提供了有价值的 为ME-INBRE合作机构的学生提供生物信息学研究培训。总而言之，核心将 提供ME-INBRE科学家需要的生物信息学方面的智力和技术专业知识和培训 完成他们的研究目标。

BIOINFORMATICS CORE PROJECT SUMMARY The Maine IDeA Network for Biomedical Research Excellence (ME-INBRE) Bioinformatics Core will support research in comparative functional genomics by providing essential consulting and training in bioinformatics. Biomedical research increasingly utilizes high throughput technologies, and the Core will provide the specialized expertise needed for managing, analyzing and interpreting large data sets. Expert Core staff will advise and/or collaborate with ME-INBRE researchers in the application of best practices in experimental design, data management, and state-of-the-art workflows for genomic data analysis, with a particular focus on rigor and reproducibility. Core personnel will also provide ME-INBRE Project Leaders access to and expertise in the use of appropriate cyberinfrastructure spanning local, regional, and Cloud computing resources. The Bioinformatics Core will leverage regional collaborations and cyberinfrastructure through the Northeast Cyberinfrastructure Consortium (NECC) that ME-INBRE cofounded with four other IDeA states to expand regional cyberinfrastructure and conduct collaborative cyber enabled research. Through the Northeast Bioinformatics Collaborative (NEBC), the Core will work with INBRE Bioinformatics Core staff in Delaware, New Hampshire, Rhode Island, and Vermont on consulting projects to support Maine faculty and collaborate on delivering bioinformatics training to faculty and students. Regional cyberinfrastructure will be used for intensive computation and centralized data storage, sharing and backup. The Core will maintain and build upon its established bioinformatics training courses and workshops, which address audiences ranging from the undergraduate level to faculty investigators, and will continue to support the University of Maine’s Professional Master’s in Bioinformatics program and Bioinformatics Scholars Program, which provide valuable bioinformatics research training for students at ME-INBRE partner institutions. In summary, the Core will provide the intellectual and technical expertise and training in bioinformatics that ME-INBRE scientists need to accomplish their research goals.