Using Implementation Science to Increase PrEP Uptake among African American Women in the South - HIV/AIDS Supplement

项目总结/摘要 这项建议是为了回应：“国家卫生和人类发展研究所艾滋病毒/艾滋病研究奖的行政补充， 经历健康差异的人群（NOT-MD-21-020）。母公司K 01奖旨在开发， 测试和评估PrEP实施工具包，供美国南部社区医疗诊所的工作人员使用， 增强美国南部非洲裔美国妇女获得PrEP的机会。为非裔美国妇女提供PrEP服务 在美国，公共卫生紧急情况和社会结构不平等可能会影响妇女的健康， 医疗保健体验和整体健康。这份行政补充文件提出了一项解释性建议， 序贯混合方法设计，以评估基于临床的干预对PrEP吸收的影响， 非裔美国女性I期：基线、2个月和4个月（N=300）至 评估干预措施对患者水平PrEP吸收的影响（目标1）。第二阶段包括个别面谈， 说明调查结果（目标2）。综合社会认知理论、社会压力理论和交叉性理论， 我们提出的混合方法研究将为干预对患者水平的影响提供重要证据 在国家突发公共卫生事件和社会结构不平等的背景下取得的成果。的结果 这一拟议的行政补充将加强临床干预影响的证据， 提高PrEP吸收在临床水平和非洲裔美国妇女患者。

Project Summary/Abstract This proposal is in response to: “Administrative Supplements to NIMHD Awards for Research on HIV/AIDS in Populations that Experience Health Disparities (NOT-MD-21-020).” The parent K01 award seeks to develop, test, and evaluate a PrEP Implementation Toolkit for staff in community healthcare clinics in the U.S. South to enhance PrEP access to African American women in the U.S. South. PrEP access for African American women in the U.S. may be disrupted by public health emergencies and sociostructural inequities influencing women’s healthcare experiences and overall wellbeing. This administrative supplement proposes an explanatory sequential mixed-methods design to assess the impact of a clinic-based intervention on PrEP uptake among African American women. Phase I: repeated cross-sectional surveys at baseline, 2- and 4-months (N=300) to assess the intervention’s impact on patient-level PrEP uptake (Aim 1). Phase II includes individual interviews to explicate survey findings (Aim 2). Integrating Social Cognitive theory, Social Stress theory and intersectionality, our proposed mixed-methods study will provide vital evidence of the intervention’s impact on patient-level outcomes within the context of national public health emergencies and sociostructural inequities. Findings from this proposed administrative supplement will strengthen the evidence of the clinical intervention’s impact to enhance PrEP uptake at both the clinic-level and among African American women patients.