Research and Mentoring Program in Improving Access to Incontinence Care for Older Adults

项目总结 这份K24职业中期研究员奖的申请将促进Alayne Markland博士的指导和 下尿路症状和尿失禁患者导向研究的职业发展 阿拉巴马大学伯明翰分校。马克兰博士是一名老年病学家和临床研究员。 致力于推进膀胱和肠道症状的预防、评估和治疗的证据 为老年女性和男性准备的。在国家老龄研究所、国家糖尿病研究所的资助下， 消化和肾脏疾病，以及退伍军人事务部，她领导着一个全国公认的， 以患者为中心的研究计划，强调改善获得护理模式的机会，以及改善 关于与衰老相关的泌尿生殖功能障碍的共同风险因素的知识。她的工作重点是 常见衰老综合征，如抑郁和功能状态，与下尿路的交集 症状和大小便失禁。到目前为止，她已经创造了照顾女性和男性的新模式，改进了 临床护理和研究中使用的患者报告的结果衡量标准，并为指导国家 和治疗下尿路症状和大小便失禁的国际指南。她也有 作为发表了高影响力研究的早期临床研究人员的成功导师， 获得了美国国立卫生研究院和退伍军人管理局资助的奖项，并继续改善以患者为导向的研究，重点是 行为干预。 在获奖支持下，马克兰博士计划通过教学和教学来扩展和完善她的指导技能 集中培训，并继续指导她目前处于早期阶段的学员，并通过 重点关注来自不同背景的女性学员。所有受训人员都将接受教育和研究 为他们的职业阶段和兴趣量身定制的经历。在获奖支持下，马克兰博士的研究计划 将通过一项新资助的临床试验来扩大，解决使用移动医疗平台来提供 下尿路症状的行为治疗和失禁护理，这将提供新的 指导学员的机会、合作和未来的资金。新研究1的目的是：确定 基于行为的移动健康平台改善下尿路症状和 大小便失禁严重。新研究2的目标是：定义使用移动医疗的障碍和促进者 改善下尿路症状和尿失禁严重程度的技术。新研究3的目的是： 为未来的移动卫生干预确定有效、可行的候选组件。长期目标 马克兰博士的研究和职业生涯有两个方面：1)成为基于行为的治疗的领导者 利用数字健康平台进行干预，以及2)提高作为以患者为导向的研究导师的技能- 特别是对妇女和少数族裔的被辅导者。通过这一奖项和所研究的新研究提出的建议。 Markland将支持有潜力成为以患者为导向的研究的领导者的高质量导师 与年龄和下尿路症状/尿失禁有关。

PROJECT SUMMARY This application for a K24 Midcareer Investigator Award will promote Dr. Alayne Markland’s mentoring and career development in patient-oriented research on lower urinary tract symptoms and urinary incontinence at the University of Alabama at Birmingham (UAB). Dr. Markland is a geriatrician and clinician investigator dedicated to advancing evidence on the prevention, evaluation, and treatment of bladder and bowel symptoms for older women and men. With funding from the National Institute on Aging, the National Institute on Diabetes, Digestive, and Kidney Diseases, and the Department of Veterans Affairs, she leads a nationally recognized, patient-oriented research program that emphasizes improving access to care models, as well as improving knowledge on shared risk factors underlying aging-associated genitourinary dysfunction. Her work focuses on the intersection of common aging syndromes, such as depression and functional status, with lower urinary tract symptoms and incontinence. To date, she has created new models of care for women and men, improved patient-reported outcome measures used in clinical care and research and provided evidence to guide national and international guidelines on the treatment of lower urinary tract symptoms and incontinence. She has also emerged as a successful mentor of early-stage clinical investigators who have published high-impact research, obtained NIH and VA-funded awards, and continues to improve patient-oriented research focused on behavioral interventions. With award support, Dr. Markland plans to expand and refine her mentoring skills through didactics and focused training, and to continue mentoring her current early-stage trainees and recruit new trainees with a focus on female trainees from diverse backgrounds. All trainees will be provided with educational and research experiences tailored to their career stage and interests. With award support, Dr. Markland’s research program will be augmented through a newly funded clinical trial addressing the use of mobile health platforms to deliver behavioral treatments for lower urinary tract symptoms and incontinence care, which will provide new opportunities for mentoring trainees, collaborations, and future funding. The Aim of New Study 1 is: Identify mechanisms by which behaviorally based mobile health platforms improve lower urinary tract symptoms and incontinence severity. The Aim of New Study 2 is: Define barriers and facilitators for using mobile health technology for improving lower urinary tract symptoms and incontinence severity. The Aim of New Study 3 is: Determine effective, feasible candidate components for future mobile health interventions. The long-term goal of Dr. Markland’s research and career is two-fold: 1) to become a leader of behaviorally-based treatment interventions with digital health platforms, and 2) to enhance skills as a mentor of patient-oriented research — particularly for women and minority mentees. Through this award and the new research studied proposed, Dr. Markland will support high-quality mentees with the potential to become leaders in patient-oriented research related to aging and lower urinary tract symptoms/incontinence.