AppalTRuST Project 3: Impact of proposed tobacco product rules in Appalachia on consumption and product switching with the Experimental Tobacco Marketplace

摘要-项目3 我们的总体目标，反映了AppalTRuST调查监管变化影响的综合主题 在肯塔基州阿巴拉契亚的烟草产品使用，是评估拟议的烟草产品法规的影响， 使用我们在过去几年中开发和完善的行为经济学方法来描述 在阿巴拉契亚肯塔基州复杂的尼古丁市场中，烟草产品的消费是多样化的， 这将大大受益于有重点的烟草监管科学研究。这 项目主要属于影响分析的监管科学领域的福尔斯。2009年，食品和药物 美国食品和药物管理局（FDA）被授权管理烟草产品，以造福公众健康。几年 自那时以来，FDA已经提出了可能有利于公共健康的潜在监管行动，包括监管 可燃香烟中的最大尼古丁含量，以及限制燃烧和非燃烧香烟的味道， 燃烧的烟草产品。估计任何拟议的监管行动的影响是复杂的， 存在一个复杂的烟草市场，其中包含多种产品，这些产品是一种产品的经济替代品 另一个原因是制造商经常推出新的烟草产品。此外，当 与更多的城市，非阿巴拉契亚社区相比，阿巴拉契亚农村社区往往有1）更高 烟草制品使用率总体上，2）不同的使用模式，包括更多的燃烧烟草制品， 以及3）烟草商店中的不同产品可用性。因此，重要的是要估计任何不同的影响 阿巴拉契亚地区烟草产品法规的提案实验烟草市场（ETM） 模型中，产品的可用性是跨群体操纵的，需求弹性和替代是 通过对烟草产品的测量，我们将估计调节1）燃烧的烟草中尼古丁含量的影响。 香烟，2）可燃香烟中的薄荷醇香料限制，以及3）非可燃香烟中的香料添加剂限制。 燃烧的尼古丁/烟草产品，包括ENDS。在两个目标中，我们将评估这些目标的影响。 阿巴拉契亚（目标1）内的三项规定，以及农村对这些拟议规定的影响， 阿巴拉契亚（目标2）。

ABSTRACT – Project 3 Our overall goal, reflecting AppalTRuST’s Integrative Theme of investigating the effects of regulatory changes on tobacco product use in Appalachian KY, is to assess the impact of proposed tobacco product regulations using behavioral economic methods that we have developed and refined in past years to characterize the consumption of tobacco products within the complex nicotine marketplace of Appalachian KY, a diverse and underserved rural region that would greatly benefit from focused tobacco regulatory science research. This project primarily falls under the Regulatory Scientific Domain of Impact Analysis. In 2009, the Food and Drug Administration (FDA) was granted authority to regulate tobacco products to benefit public health. In the years since, the FDA has proposed potential regulatory actions that may benefit public health, including regulating the maximum nicotine content in combustible cigarettes and restricting flavors of combusted and non- combusted tobacco products. Estimating the impact of any proposed regulatory action is complicated by the existence of a complex tobacco marketplace containing multiple products that are economic substitutes for one another and the frequent introduction of new tobacco products by manufacturers. Furthermore, when compared to more urban, non-Appalachian communities, rural Appalachian communities often have 1) higher rates of tobacco product use overall, 2) different use patterns that include more combusted tobacco products, and 3) different product availability in tobacco stores. It is therefore important to estimate any differential impact of proposed tobacco-product regulations in Appalachia. Using an Experimental Tobacco Marketplace (ETM) model where product availability is manipulated across groups and demand elasticity and substitution is measured across tobacco products, we will estimate the impact of regulating 1) nicotine content of combusted cigarettes, 2) menthol flavor restrictions in combustible cigarettes, and 3) flavor additive restrictions in non- combusted nicotine/tobacco products including ENDS. Across two aims, we will assess the impact of these three regulations within Appalachia (Aim 1) and the effect of rurality on impact of these proposed regulations in Appalachia (Aim 2).