Bio-Layer Interferometry (BLI) Octet R8

项目摘要/摘要 这项提案要求为八位组R8提供资金，以支持NIH机构发展奖 (IDEA)位于内华达州的中心和NIH资助的研究人员。世界上很大一部分 仪器时间将是为了解决整个校园内NIH资助的调查人员的需求 通过工程、科学和技术学院之间的跨学科合作和支持 医药。OCTET R8还将为内华达州INBRE、 神经科学卓越生物医学研究中心(COBRE)和细胞、分子 美国国立卫生研究院资助的影像中心。八重奏R8将允许研究人员执行新类型的 生物传感，药物发现和诊断，包括蛋白质-蛋白质，蛋白质-小分子， 蛋白质纳米颗粒，以及蛋白质-DNA相互作用的实时和高通量研究 潜在治疗药物的筛选和灵敏的生物分子传感应用。

Project Summary/Abstract This proposal requests funding for an Octet R8 to support NIH Institutional Development Award (IDeA) centers in the state of Nevada and NIH-funded researchers. A significant portion of the instrument time would be to address the needs of NIH-funded investigators across the campus via interdisciplinary collaborations and support between colleges of engineering, science, and medicine. The Octet R8 will also provide support for the Nevada INBRE, Integrative Neuroscience Center of Biomedical Research Excellence (COBRE) and the Cellular, Molecular Imaging Center funded by NIH. The Octet R8 will allow researchers to perform new types of biosensing, drug discovery, and diagnosis including protein-protein, protein-small molecule, protein nanoparticles, and protein-DNA interaction studies in real-time and high-throughput screening of potential therapeutics, and sensitive biomolecular sensing application.