RAPID ACCELERATION OF DIAGNOSTICS TECHNOLOGY (RADx® Tech) FOR MATERNAL HEALTH CHALLENGE

针对产妇健康挑战的快速诊断技术(RADx®Tech)将奖励高达800万美元的奖金，以加快家庭和护理点(POC)产妇健康诊断设备、可穿戴设备或其他遥感技术的开发。成功的技术将能够延长护理(例如，使个人能够获得可采取行动的健康信息，使他们能够决定何时寻求额外护理)，并最终降低在产后第一年(从分娩之日或怀孕结束之日)居住在产妇保健沙漠中的个人的严重孕产妇发病率和孕产妇死亡率(SMM/MM)。参加这项挑战的创新者将提交一份提案，详细描述他们的原型技术、预期的临床影响和继续开发的计划。这些建议将在可行性评估阶段进行审查，从中选出的获胜者将进入深度潜水评估阶段。在深度潜水阶段，医疗保健技术商业化和内容专家组成的项目组将直接与每个创新者接触，以跨定义的评估标准评估原型技术，并将与NIH合作，确定加速开发和实施的关键风险因素，并建立降低这些风险的里程碑，具体取决于NIH的最终决定。在深度潜水阶段入选的创新者将获得现金奖励，并进入技术评估阶段，在此阶段，他们将通过实物技术、临床和商业化支持快速降低技术风险，并为成功完成里程碑竞争额外的现金奖励。在技术评估阶段结束时，创新者将提交他们的技术进行独立测试和性能和可用性验证。那些技术成功完成最后阶段的创新者将获得现金奖励，并连接到NIH资助的研究网络和中心，探索自己的合作。获奖者被鼓励申请额外的NIH资金来继续开发他们的技术，但这种资金不是有保证的，并且受到相关资金机会公告的标准竞争和申请要求的约束。RADx技术促进产妇健康挑战是美国国立卫生研究院实施产妇健康和妊娠结局人人愿景(改善)倡议的一部分，该倡议支持侧重于减少孕产妇死亡的可预防原因和改善妇女在分娩前、分娩期间和分娩后的健康的研究。

The Rapid Acceleration of Diagnostics Technology (RADx® Tech) for Maternal Health Challenge will award up to $8 million in prizes to accelerate the development of home-based and point-of-care (POC) maternal health diagnostic devices, wearables, or other remote sensing technologies. Successful technologies will enable extension of care (e.g., empower individuals with actionable health information they can use to inform their decisions about when to seek additional care) and ultimately reduce severe maternal morbidity and maternal mortality (SMM/MM) for individuals residing in maternity care deserts during the first year of the postpartum period (from day of delivery or end of pregnancy). Innovators participating in this challenge will submit a proposal describing in detail their prototype technology, anticipated clinical impact, and plans for continued development. These proposals will be reviewed during the Viability Assessment Phase from which selected winners will advance to the Deep Dive Assessment Phase. During the Deep Dive Phase, a Project Team of healthcare technology commercialization and content experts will engage directly with each Innovator to assess the prototype technology across defined Evaluation Criteria and will work with NIH to identify key risk factors for accelerated development and implementation and establish milestones that mitigate these risks, subject to final decisions by NIH. Innovators selected in the Deep Dive Phase will receive a cash prize and advance to the Technology Assessment Phase where they will rapidly de-risk their technologies with in-kind technical, clinical, and commercialization support and compete for an additional cash prize for successful milestone completion. At the end of the Technology Assessment Phase, Innovators will submit their technologies for independent testing and verification of performance and usability. Those Innovators whose technologies successfully complete the final phase will be rewarded with a cash prize and connected to NIH-funded research networks and centers to explore collaborations on their own. Winners are encouraged to apply for additional NIH funding to continue development of their technologies, but such funding is not guaranteed and is subject to the standard competition and application requirements of the relevant funding opportunity announcements. The RADx Tech for Maternal Health Challenge is part of the NIH Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE) Initiative which supports research focused on reducing preventable causes of maternal deaths and improving health for women before, during, and after delivery.