Core 10: Health Literacy Core

项目摘要：健康素养 路易斯安那州临床与翻译科学健康素养(HL)核心的总体目标 洛杉矶CATS中心将向临床研究注入HL和社会健康决定因素(SDOH)以改善 并减少路易斯安那州最脆弱人群之间的差距。在上一次 在资助周期中，该核心在将HL原则嵌入临床研究项目方面非常有效， 以及洛杉矶CATS机构以外的机构，以提高患者获取、理解和使用健康信息的能力 以及参与临床试验。HL核心使洛杉矶猫科动物之间的合作成为可能 调查人员和联邦合格的保健中心以及宗教和民间组织，以便 在新冠肺炎检测和针对全球弱势人群的疫苗推广项目中注入HL原则 州政府。我们已经扩大了我们的地区和国家合作，包括与新冠肺炎相关的研究 德克萨斯大学休斯顿分校CTSA。下一个周期的具体目标是扩大我们的网络 更多洛杉矶CATS机构内外的研究人员将HL原理和SDOH纳入他们的临床 改善健康结果和缩小健康差距的研究：目标1.加强和扩大建立信任 与历史上被排斥的人群的关系，以了解他们的特定需求、障碍和战略 缩小健康差距。目标2.与洛杉矶CATS机构的调查人员合作，改善易受攻击的状况 患者对改善慢性病管理的新卫生技术的理解和使用， 在临床试验中坚持用药、预防性护理和招募，特别是在农村地区。目标3. 在洛杉矶猫内部建立网络，在我们地区和全国建立CTR和CTSA，并在 国家，为历史上被排除在外的人群(农村和市中心)提供公平的临床试验招募 社区、不同种族/族裔、LGBTQ、以前被监禁的个人)，以更全面地解决卫生问题 差异，以及SDOH，以改善健康结果。我们将通过以下方式实现这些目标：1)扩大HL培训 包括识字和在文化上适当地使用健康技术，例如关于数字的患者健康教育 平台、患者电子门户和数字应用程序，以增加与弱势群体的持续接触 人口；2)建议调查人员发展和维持与弱势群体的关系中的信任 人口和社区诊所，以及解决健康差距和提高参与度的机构 临床试验和健康结果；3)继续与洛杉矶猫内部的调查人员合作，包括 西班牙裔、农村和其他弱势群体。这些目标旨在包括广泛的网络 利益攸关方设计和评估可接受和可行的研究战略，以改善获取机会， 了解和使用卫生信息和服务，以改善弱势群体的健康。

Project Summary: Health Literacy The overarching goal of the Health Literacy (HL) Core of the Louisiana Clinical and Translational Science Center (LA CaTS) is to infuse HL, and Social Determinants of Health (SDOH) into clinical research to improve health outcomes and reduce disparities among Louisiana’s most vulnerable populations. During the previous funding cycles, the Core was highly effective in embedding HL principles in clinical research projects both within and outside LA CaTS institutions to increase patients’ ability to obtain, understand, and use health information and services as well as participate in clinical trials. The HL Core has enabled collaboration between LA CaTS investigators and Federally Qualified Health Centers, as well as faith-based and civic organizations, in order to infuse HL principles in COVID-19 testing and vaccine outreach projects targeting vulnerable populations across the state. We have expanded our regional and national collaborations to include COVID-19 related research with the University of Texas at Houston CTSA. Specific aims for this next cycle are designed to expand our network to more investigators within and outside LA CaTS institutions to include HL principles and SDOH in their clinical research to improve health outcomes and reduce health disparities: Aim 1. Enhance and expand trust-building relationships with historically excluded populations to understand their specific needs, barriers, and strategies to reduce health disparities. Aim 2. Collaborate with investigators at LA CaTS institutions to improve vulnerable patients’ understanding and use of new health technologies that improve management of chronic diseases, medication adherence, preventive care and recruitment in clinical trials, particularly in rural areas. Aim 3. Network within LA CaTS, with CTRs, CTSAs in our region and nationally, and with health agencies within the state, to provide equitable recruitment to clinical trials for historically excluded populations (rural and inner-city communities, diverse race/ethnicity, LGBTQ, formerly incarcerated individuals) to more fully address health disparities, and SDOH to improve health outcomes. We will accomplish these aims by: 1) expanding HL training to include literacy and culturally appropriate use of health technologies such as patient health education on digital platforms, patient electronic portals and digital apps to increase ongoing engagement with vulnerable populations; 2) advising investigators in developing and sustaining trust in relationships with vulnerable populations and community clinics, and agencies to address health disparities and improve participation in clinical trials and health outcomes; 3) continue to collaborate with investigators within LA CaTS to include Hispanic, rural, and other disadvantaged populations. These aims are designed to include a wide net of stakeholders to design and evaluate acceptable and feasible research strategies to improve access, understanding, and use of health information and services to improve the health of vulnerable populations.