Nest#2-Sensor Withdrawn from A Remote Module (SWARM)

这个Nest的目标是促进研究团队开发和实施可植入的 传感器。许多开发专门传感器的研究团队没有内部开发的专业知识 人体级植入物和过渡到人体受试者的测试。作为克利夫兰开放源码的一部分 模块化可互操作可植入社区(COSMIIC)，我们将简化和简化这一流程 通过开发从远程模块(SWARM)中取出的传感器来研究小组。蜂群 系统由一个传感器不可知的模块组成，即群主机，它将与任意 基于临床需求和靶向功能的边缘传感器--群传感器。作为中国商飞的一部分 生态系统中，团队可以利用集群主机、电源模块(PM)和所有其他NNP 平台硬件和软件协议，并专注于开发一种用于内部健康的新型集群传感器 监控或其他应用程序。集成刺激模块将在以下情况下实现闭环控制 临床上是合适的。该项目将因此加强其他团队的开发过程，并使 在有临床需求的人群中更快地实施。 除了便于开发外，拟议的模块化还允许在不同位置放置传感器 对于一个完整的远程模块来说是不切实际的。例如，传感器可以放置在 远端肢体测量脚和手的运动，以支持反馈控制。或者，传感器 可以被放置在体内更深的地方，心脏、肺、胃或其他器官上，作为植入的 调节自主神经功能的系统。 该项目将开发集群主机和单个集群传感器作为概念验证。这个 群主机将使用与现有远程模块相同的打包，最大限度地减少额外的开发。 在这种情况下，惯性测量单元(IMU)将被实现为群传感器；然而， 通信和供电协议将使群主机能够接收来自 未来传感器种类繁多，使该模块可用于多种应用。以下目标 将促进人类用户的翻译：目标1：开发用于通信的群主电路 并集成到一个完整的模块中。目标2：设计并制作一种群式惯性测量单元传感器 概念验证。目标3：完成全群系统的台式测试，以生成早期数据 提交可行性研究集成开发环境。 该项目将生成由主机和传感器组成的群系统。这些文档 将为其他团队开发传感器与集群系统集成创造一条途径。公开赛- 来源材料将使COSMIIC社区能够实施新的传感器，放大潜在的临床 NNP系统可以满足的需求，然后成为提高人们生活质量的产品。

The goal of this Nest is to facilitate research teams’ development and implementation of implantable sensors. Many research teams developing specialized sensors do not have the expertise in-house to develop human grade implants and to transition to testing in human subjects. As part of the Cleveland Open Source Modular Interoperable Implantable Community (COSMIIC), we will simplify and streamline this process for research groups by developing the Sensor Withdrawn from A Remote Module (SWARM). The SWARM System consists of a sensor agnostic module, the SWARM Host, that will communicate with an arbitrary outlying sensor, the SWARM Sensor, based on the clinical need and targeted function. As part of the COSMIIC ecosystem, teams can take advantage of the SWARM Host, power module (PM), and all of the other NNP platform hardware and software protocols, and focus development on a new SWARM sensor for internal health monitoring or other applications. Incorporating stimulation modules will enable closed loop control when clinically appropriate. This project will thereby enhance the development process for other teams and enable more rapid implementation in people with clinical needs. In addition to facilitating development, the proposed modularity enables sensor placement in locations of the body that would be impractical for a full remote module. For example, sensors could be placed in the distal extremities to measure foot and hand movement to support feedback control. Alternatively, sensors could be placed deeper into the body, on the heart, lungs, stomach, or other organs as part of an implanted system regulating autonomic function. This project will develop the SWARM Host and a single SWARM Sensor as a proof of concept. The SWARM Host will utilize the same packaging as existing remote modules, minimizing additional development. In this instance, an inertial measurement unit (IMU) will be implemented as the SWARM Sensor; however, the communication and powering protocols will enable the SWARM Host to receive digital or analog signals from a wide variety of sensors in the future so that the module can be used for many applications. The following Aims will facilitate translation to human users: Aim 1: Develop SWARM Host circuitry for communication with outlying sensors and integrate into a full module. Aim 2: Design and fabricate a SWARM IMU Sensor as a proof-of-concept. Aim 3: Complete bench-top testing for a full SWARM System to generate data for an early feasibility study IDE submission. This project will generate the SWARM System consisting of the Host and sensor. The documentation will create a pathway for other teams to develop sensors to integrate with the SWARM System. The open- source material will enable the COSMIIC community to implement new sensors that amplify potential clinical needs that could be met with the NNP system and then become products to improve quality of life for people.