Administrative Core

项目摘要摘要：行政核心 管理核心是使MSCP SPORE能够实现其使命和愿景的枢纽， 目前黑色素瘤和其他皮肤癌治疗中的关键问题和障碍， 结果。行政核心将提供科学和财政监督，并加强沟通 多个层次，以确保MSCP SPORE的成功。核心将监督日常运作 协调定期的行政和科学审查，并与NCI计划办公室密切合作。核心 人员将协调MSCP SPORE活动与匹兹堡大学医学中心的活动 （UPMC）希尔曼癌症中心（HCC），其教师参加MSCP的部门和学校 与外部合作机构和倡导团体合作开展的“孢子”项目。核心会培养 SPORE项目之间的相互作用以及与MSCP SPORE区域之外的相关研究， 在国内和国际上。核心将监督发展研究计划（DRP）和 职业提升计划（CEP），并发出申请新的试点项目，这些在半 每年的基础上，安排他们的审查，优先次序，并成功的DRP和CEP申请的资金。 管理核心将提供管理框架，通过该框架， 委员会，内部咨询委员会（IAB）和外部咨询委员会（EAB）以及我们的患者倡导者 可以评估项目活动，并根据需要重新分配资源，以最大限度地实现 MSCP SPORE的目标。核心将致力于提高黑色素瘤癌症的认识， 慈善支持黑色素瘤和皮肤癌研究，提升深度，增加广度 MSCP SPORE研究工作的影响。将这些工作集中到核心， 并确保在整个计划中统一遵循SPORE指南。行政核心 将监控SPORE研究项目和核心的预算，以确保不发生重复工作 MSCP SPORE与HCC的共享设施、HCC的其他受资助SPORE或国家 合作团体。核心将由三个研究项目平等使用，其他两个核心， DRP和CEP。

Project Summary Abstract: Administrative Core The Administrative Core is the hub that will enable the MSCP SPORE to fulfill its mission and vision to address key problems and barriers in current therapies for melanoma and other skin cancers, to improve patient outcomes. The Administrative Core will provide scientific and fiscal oversight and enhance communication on multiple levels to ensure the success of the MSCP SPORE. The Core will oversee day-to-day operations, coordinate periodic administrative and scientific reviews, and work closely with the NCI Program Office. Core personnel will coordinate MSCP SPORE activities with those of the University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), the Departments and Schools whose faculty participate in MSCP SPORE projects, with outside collaborating institutions, and with advocacy groups. The Core will foster interactions among SPORE projects and with related research outside the MSCP SPORE regionally, nationally, and internationally. The Core will oversee the Developmental Research Program (DRP) and the Career Enhancement Program (CEP) and issue requests for new pilot project applications for these on a semi- annual basis, arranging for their review, prioritization, and funding of successful DRP and CEP applications. The Administrative Core will provide the administrative framework through which the SPORE Executive Committee, Internal Advisory Board (IAB), and External Advisory Board (EAB) as well as our patient advocates can evaluate program activities and redirect resources as needed to maximize translational progress toward the goals of the MSCP SPORE. The Core will work to raise melanoma cancer awareness and to increase philanthropic support of melanoma and skin cancer research, to enhance the depth and increase the breadth of impact of the MSCP SPORE research effort. Centralization of these efforts in the Core maximizes efficiency and ensures that SPORE guidelines are followed uniformly throughout the program. The Administrative Core will monitor budgets of the SPORE Research Projects and Cores to ensure that no duplication of effort occurs between the MSCP SPORE and the shared facilities at HCC, other funded SPOREs at HCC, or the national cooperative groups. The Core will be used equally by the three research projects, the other two Cores, the DRP, and the CEP.