A Training Development Plan for HIV-associated Behavioural Medicine

项目描述/摘要 南非是世界上艾滋病毒负担最重的国家，估计有820万艾滋病毒感染者（PWH） 在全国艾滋病病毒的流行是由生物心理社会因素的复杂相互作用驱动的，威尔斯亲王医院 与普通精神障碍（CMD）的高共病率-一些估计表明，五分之一的PWH 证明抑郁症，创伤后应激障碍或物质使用障碍的神经病学。的 艾滋病毒和CMD的协同压力对整个艾滋病毒护理级联产生了重大的不利影响， 坚持抗逆转录病毒治疗，继续接受艾滋病毒治疗和抑制病毒。为了解决这些问题， HIV心理健康研究单位（HIV MHU）进行了NIH资助的描述性和干预性试验 研究了十多年，这导致该单位开发了一个新的硕士学位课程， 行为医学-一个新的和新兴的领域在南非。在UCT的研究和培训期间， 艾滋病毒和精神障碍的交叉点稳步增长，这些因素需要明确的凝聚力和战略 方向具体而言，拟议的培训方案打算利用现有的研究方案， 艾滋病毒卫生股建立艾滋病毒相关行为医学的研究培训能力。两年规划补助金 将使我们能够记录和分析UCT和其他南非国家现有的研究和培训能力， 与艾滋病毒相关的行为医学的大学，以确定差距和需求。此外，通过合作 与合作机构的关系，我们的目标是建立一个组织结构， Fogarty D43申请，并确定UCT的潜在受训候选人，这些候选人可以被招募参加以下培训： D43 Fogarty培训计划中的行为医学。在资助期间，我们的目标是巩固 我们的行为医学计划在单位，更广泛的大学，并与我们的国际合作者， 最终提供一套硕士，博士和博士后培训，以一个新的队列，无论是临床医生- 科学家，以及基础和社会科学家。虽然我们迄今为止的研究已经改善了艾滋病毒 治疗依从性，病毒抑制和心理健康结果，行为医学是一种新兴的， 在南非发展的领域。到目前为止，南非还没有建立行为医学方案， 专注于艾滋病、精神障碍和行为。建议的规划补助金将有助设立 在南非和非洲大陆。

Project Description/Abstract South Africa has the largest HIV burden in the world, with an estimated 8.2 million people living with HIV (PWH) in the country. The HIV epidemic is driven by a complex interaction of biopsychosocial factors, and PWH have high comorbidity with common mental disorders (CMD) – some estimates indicate that one in five PWH demonstrate symptomology for depression, post-traumatic stress disorder, or substance use disorders. The synergistic stress of HIV and CMD has significant adverse impacts across the HIV care-cascade, most notably on adherence to antiretroviral therapy, retention in HIV care, and viral suppression. To address these concerns, the HIV Mental Health Research Unit (HIV MHU) has conducted NIH-funded descriptive and intervention trial research for more than a decade, which resulted in the Unit developing a new master’s degree program in Behavioural Medicine – a novel and emerging field in South Africa. While research and training at UCT at the intersection of HIV and mental disorders has grown steadily, these elements require clear cohesion and strategic direction. Specifically, the proposed training programme intends to leverage existing research programs in the HIV MHU to build research training capacity in HIV-associated behavioural medicine. A two-year planning grant will allow us to document and analyse the existing research and training capacity at UCT and other South African universities in HIV-associated behavioural medicine to define gaps and needs. Moreover, through collaborative relationships with partnering institutions, we aim to establish an organisational structure that would support a Fogarty D43 application and identify potential trainee candidates at UCT that could be recruited for training in behavioural medicine within the D43 Fogarty training program. During the grant period, we aim to consolidate our behavioural medicine program within the Unit, the wider University, and with our international collaborators, to ultimately offer a suite of master’s, doctoral and post-doctoral training to a new cohort of both clinician- scientists, as well as basic and social scientists. While our research to date has led to improvements in HIV treatment adherence, viral suppression, and mental health outcomes, behavioural medicine is an emerging and evolving field in South Africa. To date, there are no established behavioural medicine programs in South Africa that focus on HIV, mental disorders, and behaviour. The proposed planning grant will facilitate establishing the field in South Africa and the African continent.