Multisensory integration of auditory cues for navigation

项目摘要 空间导航是一项复杂的任务，需要感官处理、整合和创建空间 地图。我们的项目试图了解听觉线索在空间导航中的作用。传统上，听觉 地标被忽视了，科学家们转而关注视觉、前庭和本体感觉线索。新的 行为学研究指出，人类有能力利用听觉里程碑进行自我运动感知、平衡和 步态。在这里，我们试图理解听觉空间地标在空间导航中的作用，通过仔细的评估 在寻的过程中对可用的感觉线索(听觉、视觉和自我运动线索)进行实验操作 任务。我们提出了两个目的来考察听觉在空间导航中的作用。在我们的第一个目标中，我们寻求 量化听觉如何与人类空间编码和导航的其他感官相结合。我们建议 在最大似然计算模型(称为最优线索组合)的框架内研究这一点 模型)。我们假设人类将以最佳的方式使用听觉信息，尽管是听觉的 与视觉线索或自动线索相比，信息对空间地图的贡献更小。在第二个目标中，我们 建议检查感觉丧失个体对听觉信息的相对权重。我们计划 要做到这一点，在急性环境中使用虚拟现实模拟视觉和自我运动感觉损伤。我们 我还计划检查患有慢性感觉丧失(长期低视力或前庭)的个人 不对称)为导航加权听觉地标。拟议的工作将对 多感官整合领域，并有助于为遭受痛苦的个人制定潜在的新康复策略 来自感官损伤。

Project Summary Spatial navigation is a complex task that requires sensory processing, integration, and the creation of a spatial map. Our project seeks to understand the role of auditory cues in spatial navigation. Traditionally, auditory landmarks have been ignored with scientists looking instead at visual, vestibular, and proprioceptive cues. New behavioral studies point to a human ability to use auditory landmarks in self-motion perception, balance, and gait. Here, we seek to understand the role of auditory spatial landmarks in spatial navigation, assessed by careful experimental manipulation of available sensory cues (auditory, visual, and self-motion cues) during a homing task. We propose two aims to examine the role of audition in spatial navigation. In our first aim, we seek to quantify how audition is integrated with other senses for human spatial encoding and navigation. We propose to examine this in the framework of the maximum likelihood computational model (termed optimal cue-combination model). We hypothesize that humans will use auditory information in an optimal manner, though auditory information will contribute less to the spatial map than visual cues or self-motion cues. In the second aim, we propose to examine the relative weight that individuals with sensory loss place on auditory information. We plan to do this with virtual reality simulations of visual and self-motion sensory impairment in the acute setting. We also plan to examine how individuals having a chronic sensory loss (longstanding low vision or vestibular asymmetry) weight auditory landmarks for navigation. The proposed work will have a significant impact on the field of multisensory integration and help generate potential new rehabilitation strategies for individuals suffering from sensory impairment.