Arsenicals in infant foods

项目总结 本补编(PA-21-071)的目的是“通过招聘来增强研究人员的多样性 和支持学生….包括那些被证明在健康方面代表性不足的群体- 相关研究“。Aarthi Annamalai将成为正在进行的NIEHS项目的实习生(R03ES034194：“评估 低浓度二甲基砷酸暴露的时间和持续时间对其命运、代谢和发展的影响 神经发育和神经退化生物标志物)。Annamalai女士是女性，第一代 马来西亚裔美国学生，目前就读于德克萨斯理工大学微生物学专业。女士。 Annamalai将于2024年春季毕业，她的目标是在与她一起毕业后开始她的医学学位课程 B。在拟议的研究计划中，这是母项目的合理延伸，Annamalai女士将 在Amrika博士的监督下评估婴儿食品中普遍存在的总砷和砷物种 Deonarine和Jeremy Bailoo(家长赠款的PI)。该项目将把父母赠款的范围从 综合评价常用婴幼儿食品中砷形态的活体动物模型 在FDA的总饮食研究中确定。Annamalai女士将利用她在发育生物学和 环境化学解决与病理结果相关的环境毒理学中的实际问题 在童年时。Annamalai女士将有机会在全国会议上介绍她的工作，并将学习 如何撰写和发表一篇研究文章。通过这个项目，Annamali女士将学习批判性思维，发展 实验技能，并进行独立研究。整个培训计划将为 她致力于解决因接触环境毒素而产生的当代医学问题，例如 砷。

PROJECT SUMMARY The purpose of this supplement (PA-21-071) is to “enhance the diversity of the research workforce by recruiting and supporting students….including those from groups that have been shown to be underrepresented in health- related research”. Aarthi Annamalai will be a trainee on the on-going NIEHS project (R03ES034194:”Evaluation of the timing and duration of low level dimethylarsinic acid exposure to its fate, metabolism, and development of neurodevelopmental and neurodegenerative biomarkers). Ms. Annamalai is a female, first generation Malaysian-American student, currently enrolled in the Microbiology program at Texas Tech University. Ms. Annamalai will graduate in Spring 2024 and aims to start her medical degree program after graduating with her BS. In the proposed research plan, which is a reasonable extension of the parent project, Ms. Annamalai will evaluate total arsenic and arsenic species prevalent in infant foods under the supervision of Drs. Amrika Deonarine and Jeremy Bailoo (PIs of the parent grant). The project will extend the scope of the parent grant from an in vivo animal model to a comprehensive evaluation of arsenic speciation of commonly consumed infant foods identified in the FDA’s Total Diet Study. Ms. Annamalai will utilize her knowledge of developmental biology and environmental chemistry to solve real problems in environmental toxicology in relation to pathological outcomes in childhood. Ms. Annamalai will have the opportunity to present her work at a national conference and will learn how to write and publish a research article. Through this project, Ms. Annamali will learn critical thinking, develop experimental skills, and conduct independent research. The entire training program will provide a platform for her to address contemporary medical issues as a consequence of exposure to environmental toxins, such as arsenic.