Linking Innate with Adaptive Immune Response

描述(申请人提供)：先天免疫系统提供了抵御病原体的第一道防线，并在控制和指导适应性免疫方面发挥着关键作用。这一界面是2001年1月举行的一次非常成功的Keystone研讨会的主题，也是过去几年在《自然》和《科学》等杂志上发表的一系列评论、新闻和观点以及研究文章的主题。除了对微生物的反应有重要意义外，这个主题还引起了其他免疫学领域的科学家的主要兴趣，包括肿瘤免疫学、自身免疫学和疫苗开发。会议将重点介绍提供初始宿主反应和控制适应性免疫的细胞、受体、信号转导途径和可溶性介体的研究新前沿。邀请包括分子生物学家、生物化学家和细胞免疫学家在内的顶级研究人员组成的多学科小组讨论新兴概念、新技术和新的研究途径。对于为未来研究和挑战寻找机会的学生和博士后研究员来说，这次会议将特别有意义。

DESCRIPTION (provided by applicant): The Innate Immune System provides the first line of defense against pathogens, and plays a critical role in controlling and instructing Adaptive Immunity. This interface was the topic of a highly successful Keystone Symposium that was held in January, 2001 as well as a series of Reviews, News and Views and Research Articles in journals such as Nature, and Science, in the past few years. In addition to having significance to responses to microorganisms, the topic is of major interest to scientists in other areas of immunology including Tumor Immunology, Autoimmunity and Vaccine Development. The meeting will highlight the new frontiers of research on the cells, receptors, signal transduction pathways, and soluble mediators of innate immunity that provide initial host responses and that control adaptive immunity. A multidisciplinary group oftop ranking researchers including molecular biologists, biochemists and cellular immunologists is invited to discuss emerging concepts, novel technologies and new avenues of research. This meeting will be especially rewarding for students and postdoctoral fellows in search of opportunities for future research and challenges.