2006 Mechanisms in Toxicity Gordon Research Conference

描述（由申请人提供） 毒性戈登研究会议的机制在传播和促进毒理学研究方面形成了丰富的优秀传统。2006年将庆祝毒性机制会议五十周年和戈登研究会议七十五周年。该会议自1956年以来每半年举行一次，已成为关注化学损伤分子机制和环境人类疾病发病机制的首要科学会议。2006年将讨论的专题包括：一）糖原合成酶激酶3 β磷酸化：风险和益处;二）异生物质生物活化和毒性的化学机制;三）泛素蛋白体系统;四）转运蛋白：在异生物质处置和毒理学中新出现的重要蛋白质;五）核细胞质运输机制;六）线粒体介导的代谢疾病;七）成人疾病的胎儿基础;和vii）介导器官系统毒性的细胞-细胞相互作用。该计划包括国际公认的领导人和来自美国和国外的有才华的新调查人员。时间已分配给初级研究人员介绍他们的工作在最新突破的研究和海报会议。主席和共同主席将促进讨论和科学对话，以最大限度地扩大参与，并增加高级和初级调查人员、博士后研究员和研究生之间的互动。2006年毒性戈登研究会议的组织机制包括毒理学领域的最新信息，并将继续其作为毒理学领域领先的小型会议的悠久传统。

DESCRIPTION (provided by applicant) The Mechanisms of Toxicity Gordon Research Conference has developed a rich tradition of excellence in the dissemination and promotion of research in the toxicological sciences. The fiftieth anniversary of the Mechanisms of Toxicity conference and the seventy-fifth year of the Gordon Research Conferences will be celebrated in 2006. This conference has been held biannually since 1956 and has become the premier scientific meeting focusing on the molecular mechanisms of chemical injury and the pathogenesis of environmental human disease. The topics to be covered in 2006 include i) Glycogen Synthetase Kinase 3 Beta Phosphorylation: Risks and Benefits; ii) Chemical Mechanisms of Xenobiotic Bioactivation and Toxicity; iii) Ubiquitin Proteosome System; iv) Transporters: Proteins of Emerging Importance in Xenobiotic Disposition and Toxicology; v) Mechanisms of Nucleocytoplasmic Trafficking; vi) Mitochondrial Mediated Metabolic Diseases; vii) Fetal Basis of Adult Disease; and vii) Cell-cell Interactions that Mediate Organ System Toxicity. The program includes internationally recognized leaders and talented new investigators from the United States and abroad. Time has been allotted for junior investigators to present their work in late breaking research and poster sessions. Chairs and co-Chairs will stimulate discussion and scientific dialogue to maximize participation and increase interactions among senior and junior investigators, postdoctoral fellows and graduate students. The 2006 Mechanism of Toxicity Gordon Research Conference has been organized to include the latest information in the field of toxicology and will continue its long tradition as the leading small conference in toxicology.