Bioinformatics and Genomics Core

弗吉尼亚理工大学的弗吉尼亚生物信息学研究所(VBI)提议担任 大西洋中部地区生物信息学/基因组学核心研究设施。VBI是由 作为世界级生物信息学研究中心和共享资源的弗吉尼亚州联邦及其 研究项目的中心是疾病三角，即宿主-病原体-环境相互作用。因此， VBI通过全面的定量测量，科学地专注于病理系统生物学 生命系统的分子组成。具体地说，为了服务于基因组学核心组成部分，VBI将 为生物样本的DNA分析提供高性能的实验室基础设施， 核糖核酸、蛋白质和代谢物，由VBL·S核心实验室提供。作为生物信息学的核心， VBI将通过VBL·S核心提供高性能计算和信息管理需求 计算设施及其将演进、部署和支持VBL·S软件信息系统 病理系统生物学-称为PafhPorf，由国防部资助的项目-实现数据采集、存储、 为RCE成员和其他成员进行分析、管理和集成。最后，VBI将对其进行培训和教育 关于计算和信息系统用于其RCE研究的RCE研究项目支持者 目标。

The Virginia Bioinformatics Institute (VBI) at Virginia Tech proposes to serve as the Bioinformatics/Genomics Core Research Facility for the mid-Atlantic RCE. VBI was created by the Commonwealth of Virginia as a world-class bioinformatics research center and a shared resource and its research programs center on the ¿disease triangle¿, or host-pathogen-environment interactions. Thus, VBI is scientifically focused on pathosystems biology, through comprehensive quantitative measurements of molecular components of living systems. Specifically, to serve the genomics core component, VBI will provide high-performance laboratory infrastructure for analysis of biological samples with respect to DNA, RNA, proteins and metabolites via VBl¿s Core Laboratory Facility. To serve as the bioinformatics core, VBI will provide high-Performance computational and information management needs via VBl¿s Core Computational Facility and it will evolve, deploy and support VBl¿s software information system for PathoSystems Biology-called PafhPorf, a DOD-funded project-to enable data acquisition, storage, analysis, curation, and integration for the RCE members and beyond. Finally, VBI will train and educate RCE research project constituencies on computing and information systems use for their RCE research objectives.