Microbial Restoriation in Crohn's Disease: A Randomised Trial of Faecal Microbial Transplanatation in Crohn's Disease

克罗恩病会引起炎症和消化道损伤。令人信服的证据表明，肠道中的细菌在疾病的发生中发挥着重要作用。通过给患者服用健康的粪便来改变肠道细菌，粪便微生物区系移植(FMT)是安全的，也可能是有效的。这项安慰剂对照试验将确定FMT(胶囊给药)是否能控制克罗恩病的炎症。结果将改变目前的治疗模式。

Crohn's disease causes inflammation and damage to the digestive tract. Compelling evidence suggests that the bacteria in the gut play an important role in the onset of disease. Changing the gut bacteria through the administration of healthy stool to a patient, faecal microbiota transplantation (FMT), is safe and may be effective. This placebo controlled trial will determine whether FMT (delivered via capsule) can control inflammation in Crohn's. Results will change current treatment paradigms.