Nitrite as a Source of Bioactive Nitric Oxide

方案进展：34例患者符合本方案的资格标准并同意。研究中有两位中途退出；一个是因为不愿意继续节食，第二个是因为在测试的早晨胸痛，作为SAE报告给IRB（两者都在2005年的持续审查中报告）。在所有其他情况下，饮食的依从性非常令人满意，并且按照方案规定进行了测量。

Protocol Progress: 34 patients met eligibility criteria for this protocol and were consented. There have been two drop-outs from the study; one because of unwillingness to continue with diet and the second because of chest pain on the morning of testing, reported to the IRB as an SAE (both reported at the 2005 continuing review). In all others, compliance with diet was highly satisfactory and measurements were performed as stipulated in the protocol. Reasons for Continuation of Protocol: We have permission to enroll 42 patients into this protocol in order to achieve 36 analyzable studies and we expect to achieve full enrollment during the coming year. The hypothesis posed in this study remains important, as the determination of dietary sources of NO may have important implications in the management of patients with atherosclerotic cardiovascular disease.