Membrane Transport Proteins Gordon Research Conference

描述(由申请者提供)：本申请请求对2008年和2010年戈登膜运输蛋白研究会议(GRC)提供部分支持。这是一个非常成功的GRC，专注于在一组不同的ATPase、离子通道和转运体中的最新发现。会议特别强调在通常不互动的研究人员之间建立科学和协作的联系，并将年轻的研究人员带入运输蛋白质领域。2008年会议将是该小组的第6次会议，并将继续强调运输蛋白在其正常生理环境中的作用以及它们在各种疾病状态中的作用(S)。该计划是完全国际化的，2008年的会议将有40名研究人员(25名来自美国，15名来自欧洲和日本)，涵盖广泛的主题，包括：大脑中的葡萄糖运输，健康和疾病中的Trp通道，膜转运体的运输，多重耐药和抗微生物，抗癌和抗癫痫化合物，膜转运体的结构，膜转运体的中枢神经系统疾病，重金属离子传输，膜运输和代谢传感，以及生物技术：分子传感器。上一次会议决定每两年在美国和欧洲的会场之间轮换一次，以努力让更多的研究人员，特别是研究生和博士后研究员从经济上接触到这次会议，这突显了这次会议的国际范围。我们预计在每次会议上至少支持25名年轻调查人员，并将积极寻求业界和私人基金会的支持，以推动这一目标。特别强调选择妇女和少数群体发言者，并制定了招募少数群体参与者的计划。会议将遵循成熟的GRC模式，强调老牌科学家之间以及老牌科学家和年轻研究人员之间的互动。这些膜运输蛋白会议的有效性将使用由GRC教职员工开发的完善的调查问卷进行评估。过去的五次会议都得到了很高的评价；2006年会议的与会者中，超过90%的人将其评为“当年他们参加的最好的会议”，并表示这些演讲在“科学前沿”上“发人深省、激动人心、激动人心”。2008年会议的举办地是意大利的Il Ciocco，靠近交通便利的卢卡(25英里)、比萨(39英里)和佛罗伦萨(74英里)。该场地拥有现代化的设施，非常适合小型GRC风格的会议。提供了足够的空间，使海报可以在多天内使用，从而进一步便利了年轻调查员和老牌调查员之间的互动。根据轮流开会的决定，2010年会议的地点暂定在缅因州的新英格兰大学。

DESCRIPTION (provided by applicant): This application requests partial support for the 2008 and 2010 Gordon Research Conferences (GRC) on Membrane Transport Proteins. This is a highly successful GRC that focuses on recent discoveries in a diverse group of ATPases, ion channels and transporters. The Conference places particular emphasis on developing connections, both scientific and collaborative, between investigators who do not normally interact and on bringing young investigators into the transport protein field. The 2008 Conference will be the 6th meeting of this group and will continue to stress the role of transport proteins in both their normal physiologic setting and their role(s) in a wide variety of disease states. The program is fully international, the 2008 meeting will feature 40 investigators (25 from the USA, 15 from Europe and Japan) covering a wide range of topics including: Glucose Transport in the Brain, TRP Channels in Health and Disease, Trafficking of Membrane Transporters, Multiple Drug Resistance and Anti-microbial, Anti-cancer and Antiepileptic Compounds, Structure of Membrane Transporters, CNS Diseases of Membrane Transporters, Heavy Metal Ion Transport, Membrane Transport and Metabolic Sensing, and Biotechnology: Molecular Sensors. The international scope of this conference is emphasized by the decision at the last meeting to alternate every two years between venues in the US and Europe in an effort to make the conference financially accessible to more investigators, particularly graduate students and post doctoral fellows. We expect to support a minimum of 25 young investigators at each meeting and will actively seek support from both industry and private foundations to further this goal. Particular emphasis has been placed on selecting both women and minority speakers and a plan is in place to recruit minority participants. The meetings will adhere to the well developed GRC format which emphasizes interaction between established scientists and between established scientists and young investigators. The effectiveness of these Membrane Transport Protein conferences will be evaluated using the well established questionnaires developed by the GRC faculty. The past five conferences have rated high marks; greater than 90% of the participants in the 2006 conference rated it as the "best conference they attended that year" and indicated the presentations were 'thought provoking, stimulating and exciting' at the 'frontiers of science'. The venue for the 2008 Conference is Il Ciocco, Italy close to convenient transportation sites, Lucca (25 miles), Pisa (39 miles) and Florence (74 miles). The site has modern facilities ideally suited to small GRC style meetings. Sufficient space is provided to have posters available for multiple days thus further facilitating interactions between younger and established investigators. In keeping with the decision to alternate meetings, the venue for the 2010 conference is tentatively planned to be at the University of New England in Maine.