ANTICYTOKINE AUTOANTIBODIES/GROWTH FACTORS IN RARE LUNG DISEASES
ANTICYTOKINE AUTOANTIBODIES/GROWTH FACTORS IN RARE LUNG DISEASES
批准号:
7607760
负责人:
Bruce C Trapnell
金额:
$2.56万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-02-15 至 2007-11-30
关键词:
AntibodiesAutoantibodiesBloodBlood donorClinical ResearchComputer Retrieval of Information on Scientific Projects DatabaseDevelopmentDiseaseEligibility DeterminationFundingGrantGrowth FactorHealthIndividualInstitutionLung diseasesMedicalMinimal Risk StudyNeedlesNursesPlayPurposeQuestionnairesRecruitment ActivityResearchResearch PersonnelResourcesRoleSourceSterilityUnited States National Institutes of Healthagedresearch study
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目及
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者的研究机构。
本研究的目的是从正常健康的献血者中采集血液。 研究收集的血液,以确定血液中发现的某些抗体和其他因素如何通过比较正常,健康的血液与患有这些疾病的个体中发现的血液在罕见肺部疾病的发展中发挥作用。 每年将招募约50名受试者,持续3年。 本研究是一项无潜在直接获益的最低风险研究。 符合献血标准的18至40岁的正常健康献血者有资格参加。 献血者填写一份医疗健康和献血者问卷,在参与之前进行审查,以核实合格性。 血液由综合临床研究中心的护士抽取。 使用无菌一次性针头采集约30 ml血液。 捐助者的参与得到补偿。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The purpose of the research study is to collect blood from normal, healthy donors. The blood collected is studied to determine how certain antibodies and other factors found in the blood can play a role in the development of rare lung diseases by comparing normal, healthy blood to the blood found in individuals with these diseases. Approximately 50 subjects will be recruited annually for three years. The study is a minimal risk study without potential direct benefit. Normal healthy donors aged 18 to 40 that meet criteria to donate blood are eligible to participate. Donors complete a medical health and blood donor questionnaire, which are reviewed prior to participation to verify eligibility. The blood is drawn by nurses in the General Clinical Research Center. A sterile, single use needle is used to collect approximately 30 ml of blood. Donors are compensated for their participation.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Retrospective Autoimmune PAP Natural History and Patient-Reported Outcomes Study
-
批准号:10571074
-
项目类别:
-
资助金额:$30.0万
-
财政年份:2022
-
负责人:Bruce C Trapnell
-
依托单位:
Macrophage Based Gene Therapy for Hereditary Pulmonary Alveolar Proteinosis
-
批准号:8725410
-
项目类别:
-
资助金额:$66.83万
-
财政年份:2014
-
负责人:Bruce C Trapnell
-
依托单位:
RLDC: Molecular Pathway-Driven Diagnostics & Therapeutics for Rare Lung Diseases
-
批准号:8765116
-
项目类别:
-
资助金额:$93.75万
-
财政年份:2014
-
负责人:Bruce C Trapnell
-
依托单位:
Macrophage Based Gene Therapy for Hereditary Pulmonary Alveolar Proteinosis
-
批准号:8842699
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项目类别:
-
资助金额:$68.86万
-
财政年份:2014
-
负责人:Bruce C Trapnell
-
依托单位:
RLDC: Molecular Pathway-Driven Diagnostics & Therapeutics for Rare Lung Diseases
-
批准号:9140225
-
项目类别:
-
资助金额:$22.78万
-
财政年份:2014
-
负责人:Bruce C Trapnell
-
依托单位:
RLDC: Molecular Pathway-Driven Diagnostics & Therapeutics for Rare Lung Diseases
-
批准号:9114659
-
项目类别:
-
资助金额:$62.5万
-
财政年份:2014
-
负责人:Bruce C Trapnell
-
依托单位:
RLDC: Molecular Pathway-Driven Diagnostics & Therapeutics for Rare Lung Diseases
-
批准号:9321931
-
项目类别:
-
资助金额:$62.5万
-
财政年份:2014
-
负责人:Bruce C Trapnell
-
依托单位:
Macrophage-based Human Gene Therapy for Hereditary PAP
-
批准号:8031206
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项目类别:
-
资助金额:$19.09万
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财政年份:2010
-
负责人:Bruce C Trapnell
-
依托单位:
Macrophage-based Human Gene Therapy for Hereditary PAP
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批准号:8206634
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项目类别:
-
资助金额:$21.88万
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财政年份:2010
-
负责人:Bruce C Trapnell
-
依托单位:
Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAP
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批准号:10153849
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项目类别:
-
资助金额:$39.75万
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财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of GM-CSF in Myeloid Cell Function and Innate Immunity
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批准号:8108866
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项目类别:
-
资助金额:$38.22万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of GM-CSF in Myeloid Cell Function and Innate Immunity
-
批准号:8645691
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项目类别:
-
资助金额:$36.79万
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财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of GM-CSF in Myeloid Cell Function and Innate Immunity
-
批准号:8249367
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项目类别:
-
资助金额:$37.54万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of GM-CSF in Myeloid Cell Function and Innate Immunity
-
批准号:8443407
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项目类别:
-
资助金额:$35.73万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAP
-
批准号:10609498
-
项目类别:
-
资助金额:$39.75万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of GM-CSF in Myeloid Cell Function and Innate Immunity
-
批准号:8819142
-
项目类别:
-
资助金额:$36.97万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of Anti-GM-CSF Antibodies in Myeloid Cell Function & Innate Immunity
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批准号:7264359
-
项目类别:
-
资助金额:$37.5万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAP
-
批准号:9476360
-
项目类别:
-
资助金额:$39.0万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAP
-
批准号:10401782
-
项目类别:
-
资助金额:$39.75万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
Role of Anti-GM-CSF Antibodies in Myeloid Cell Function & Innate Immunity
-
批准号:7581037
-
项目类别:
-
资助金额:$37.5万
-
财政年份:2007
-
负责人:Bruce C Trapnell
-
依托单位:
海外基金