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Modified peanut allergen combined with a novel dietary adjuvant as a cure for peanut allergy: a randomised controlled trial

Modified peanut allergen combined with a novel dietary adjuvant as a cure for peanut allergy: a randomised controlled trial
改良花生过敏原与新型膳食佐剂联合治疗花生过敏:一项随机对照试验
批准号:
nhmrc : 1104134
负责人:
Dr Julie Clarke
金额:
$77.85万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2019-12-31

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中文摘要
翻译
花生过敏很常见,而且无法治愈。目前对花生免疫疗法的研究表明,其效果通常不会持续很长时间,而且有很多副作用。我们计划研究一种新的口服花生免疫疗法,使用改性花生和膳食纤维(改性淀粉)补充剂。我们有证据表明,改良过的花生可以使病人脱敏,副作用更小,而且这种膳食补充剂可以保护动物免受食物过敏的影响。
英文摘要
Peanut allergy is common and there is no cure. Current studies of peanut immunotherapy have shown the effects are not generally long lasting with many side effects. We plan to study a novel form of oral peanut immunotherapy using modified peanut and a dietary fibre (modified starch) supplement. We have evidence that modified peanut may work to desensitise patients with less side effects and that the diet supplement protects animals from developing food allergy.
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