DEPO MEDROXYPROGESTERONE ACETATE (DMPA) USE IN OBESE AND MORBIDLY OBESE WOMEN

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是确定醋酸甲羟孕酮（DMPA）在肥胖和病态肥胖妇女中的致糖尿病和致脂肪生成作用。我们将通过比较DMPA使用4.5个月前后的IVGTT、OGTT、DEXA扫描、血脂、瘦素、CRP和脂联素结果来实现这一点。这项初步研究将有助于了解这种避孕药在肥胖和移动性肥胖妇女中的作用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine the diabetogenic and lipogenic effects of Depo Medroxyprogesterone Acetate (DMPA) use in the obese and morbidly obese women. We will accomplish this by comparing IVGTT, OGTT, DEXA scan, Lipid panel, Leptin, CRP, and Adinponectin results before and after 4.5 months of DMPA use. This pilot study wil;l be instrumental in the understanding effects of this contraceptive agent in obese and mobidly obese women.