GLYCEMIC LOAD AND FETAL GROWTH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项随机对照喂养研究。参与者，60名年龄在25岁或以上的糖耐量受损的女性，将从BIDMC的门诊招募。在通过口服葡萄糖耐量测试确认符合条件后，受试者将被分配到低血糖负荷饮食或传统饮食，以满足所有当前的营养建议，以实现怀孕期间的最佳健康。主要终点将是后代的出生体重；流程/遵从性措施将是未经宣布的24小时饮食召回；次要终点将包括母亲体重增加、母亲的代谢综合征成分以及婴儿的肥胖症和脐带血分析。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a randomized controlled feeding study. Participants, 60 women age 25 years or older with impaired glucose tolerance, will be recruited from the outpatient clinics at BIDMC. After confirming eligibility by an oral glucose tolerance test, subjects will be assigned to either a low glycemic load diet or a conventional diet designed to satisfy all current nutritional recommendations for optimal health during pregnancy. The primary endpoint will be birth weight of the offspring; the process/compliance measure will be unannounced 24-hour dietary recall; secondary endpoints will include maternal weight gain, metabolic syndrome components in the mother, and adiposity and cord blood analysis in the infant.