Ultra-wide Field-of-View Endoscope for White Light and Narrow Band Imaging

描述（由申请人提供）：内窥镜可视化对于微创手术至关重要。然而，当前内窥镜成像技术的已知局限性包括有限的视场以及不令人满意的特异性和灵敏度。InterScience在此提出了一种全方位内窥镜系统，具有白色光和窄带成像能力，基于我们已获得专利和正在申请专利的C-ViewTM光学技术，允许围绕光轴高达120度的宽视场和360度的立体角（3@球面立体角）。除了正常的白色光观察外，所提出的系统还提供窄带成像功能（用窄的红色、绿色或蓝色光带照明），目标是帮助早期检测微小病变（如癌症）和术前准确诊断病变区域。它还将提供粘膜表面病变和毛细血管特征变化的增强图像，以及粘膜和粘膜深处血管的轻微增厚-通过控制所用光波长。所提出的内窥镜的前所未有的宽视场将极大地改善成像覆盖范围和一致性而无需图像配准，以及增加特异性和手术彻底性，同时最大限度地减少手术时间和由各种斜面内窥镜的术中交换引起的对患者的创伤。第一阶段的工作包括成像光学设计、照明设计、初步电气设计、图像处理算法开发，以及一些现成组件的研究和测试。公共卫生相关性：项目叙述具有前所未有的视野（大于半球）和白色光和窄带成像功能的内窥镜将为临床医生提供更具体的信息，用于异常诊断，并且将比目前现有的内窥镜系统更有利于辅助微创手术。

DESCRIPTION (provided by applicant): Endoscopic visualization is of primary importance for minimally invasive procedures. However, known limitations of current endoscopic imaging technology include the limited field-of-view, and unsatisfactory specificity and sensitivity. InterScience hereby proposes an omnidirectional endoscopic system with both white light and narrow band imaging capability, based on our patented and patent pending C-ViewTM optical technology, allowing a broad field-of-view up to 120 degrees about the optical axis and 360 degrees panoramically (3@ steradian solid angle). In addition to normal white light observation, the proposed system offers narrow band imaging function (illuminated with narrowed red, green, or blue bands of light), targeting to assist the early detection of minute lesions such as cancer and preoperative accurate diagnosis of diseased areas. It will also deliver enhanced images of characteristic changes of lesions and capillary vessels in the mucosal surface, and slight thickening of the mucosa as well as vessels deep in the mucosa - by controlling the wavelength of light used. The unprecedented wide field- of-view of the proposed endoscope would greatly improve imaging coverage and consistency without image registration, as well as increase the specificity and procedure thoroughness while minimizing procedure time and trauma to the patient induced by intra-procedural swapping of various beveled scopes. The Phase I efforts include imaging optics design, illumination design, preliminary electrical designs, image processing algorithm development, plus the studies and tests of some off-the-shelf components. PUBLIC HEALTH RELEVANCE: Project Narrative The endoscope with an unprecedented field-of-view (larger than a hemisphere), and white light and narrow band imaging functions will present much more specific information to clinicians for abnormalities diagnosis, and will be more advantageous to assist minimum invasive procedures than currently existing endoscopic systems.