Maintain and update the NIA Primate Aging Database
Maintain and update the NIA Primate Aging Database
批准号:
7728691
负责人:
金额:
$11.02万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-09-01 至 2009-08-31
中文摘要
灵长类老化数据库(PAD)是一个可搜索的数据库,用于分析非人类灵长类(NHP)中与年龄相关的生物标记物。目前,该数据库包含来自11个不同机构的20个物种的数据,包括2902个动物个体和超过50万个数据点。大约80%的数据来自恒河猴。目前的数据字段主要是寿命、身体成分参数和血液化学参数,但也可以添加其他参数。通过提供与年龄相关的健康和生物标志物变化的基线信息,PAD将有助于分析正常衰老过程中的物种差异、正常衰老和与年龄相关的病理的生物标记物,以及老年灵长类动物的群体维持。
英文摘要
The Primate Aging Database (PAD) is a searchable database developed to allow analysis of age-related biomarkers in non-human primates (NHP). Currently, the database contains data from 20 species at 11 different institutions, comprising 2902 individual animals and over 500,000 data points. About 80% of the data is from rhesus monkeys. Current data fields are primarily lifespan, body composition parameters, and blood chemistry parameters, although addition of other parameters is possible. The PAD will be useful for analyses of species differences in normal aging processes, biomarkers of normal aging and age-related pathologies, and colony maintenance of geriatric primates by providing baseline information on age-related health and biomarker changes.
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