STANDING AND TRANSFERS AFTER SCI WITH AN IMPLANTED NEUROPROSTHESIS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是证明手术植入的功能性电刺激（FES）系统的安全性、有效性和功能性，该系统允许选定的脊髓损伤患者进行锻炼、站立和枢轴转移。 它还将允许向其他康复场所转让技术，使更多的人能够使用该系统。 这项研究涉及一个类似心脏起搏器的人工植入系统。 植入物将从佩戴在腰带上的外部控制单元接收信息，并将电刺激发送到连接到背部，大腿和臀部肌肉的电极。 该脉冲由控制单元上的开关控制。 通过开关控制，控制单元将发送脉冲，使肌肉收缩以执行功能性运动或锻炼。 本研究的候选人将包括患有C6-T12脊髓损伤（SCI）6个月的患者，这些患者至少18岁，双腿肌张力和痉挛，并且没有急性骨科或医学并发症。将在手术植入后3、6和12个月测量肌肉耐力和力量，以及患者对其整体健康状况、生活质量、站立和转移能力以及对系统的满意度的感知。'

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goals of this research study are to prove the safety, effectiveness and functionality of a surgically- implanted functional electrical stimulation (FES) system that allows selected individuals with a spinal cord injury to exercise, stand, and pivot transfer. It will also allow for the transfer of technology to other rehabilitation sites for more people to gain access to the system. This study involves a surgically-implanted system much like a heart pacemaker. The implant will receive information from an outside control unit worn on a waist belt and send the electrical stimulation to the electrodes which are attached to the back, thigh and buttock muscles. This impulse is controlled by a switch on the control unit. Controlled by a switch, the control unit will send impulses that cause the muscles to contract to perform functional movements or to exercise. Candidates for this study will include those persons with C6-T12 spinal cord injury (SCI) of e 6 months duration who are at least 18 years old, have muscle tone and spasticity in both legs, and have no acute orthopedic or medical complications. Muscle endurance and strength will be measured at 3, 6 and 12 months after surgical implantation, as well as the person's perception of their overall health, quality of life, ability to stand and transfer, and satisfaction with the system.'