THROMBOPHILIC ABNORMALITIES PREDISPOSING TO ARTERIAL AND VENOUS THROMBOEMBOLISM

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是调查血栓形成倾向（形成血栓的倾向）的多个方面。 这些方面包括人口统计学、遗传学和环境因素，这些因素导致血液凝固（也称为血栓形成），以及血栓形成的诊断和治疗。 参与者将被发现患有凝血障碍。 由于遗传因素通常与凝血障碍有关，因此对血栓形成患者家庭成员的研究可以提供有价值的信息。 此外，比较研究需要没有任何凝血问题的健康个体。 血栓形成项目的主要目标是利用从许多不同人群（包括有凝血问题和无凝血问题的人群）收集的信息和血液样本，制定新的策略来评估和治疗凝血异常的人群。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to investigate many aspects of thrombophilia (tendency to form blood clots). These aspects include demographic, genetic and environmental factors indlueincing blood clotting (also called thrombosis), as well as the diagnosis and treatment of thrombosis. Participants will have been found to have a clotting disorder. Because genetic (hereditary) factors are often involved in clotting disorders, the study of family members of patients with thrombosis can provide valuable information. In addition, healthy individuals without any clotting problems are needed for comparison studies. A primary goal of the UNC Thrombophilia Program is to use information and blood samples collected from many differenct people, including those with and without clotting problems, to develop new strategies for evaluating and treating people with abnormal blood clotting.