TRANSGENIC ANIMAL CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 转基因动物核心设施（TACF）作为新项目的概念和执行的核心分子生物学资源，并提供资源，以帮助抵消开发基因工程小鼠的高成本。TACF的目标是为西弗吉尼亚大学，布兰切特洛克菲勒神经科学研究所和国家职业安全与健康研究所的工作人员提供独特的研究工具。TACF目前提供转基因生产，嵌合体生产，小鼠品系再衍生，小鼠胚胎冷冻保存和小鼠胚胎复苏。在项目开发和生产的各个阶段，TACF的工作人员都可以提供教育，帮助和咨询。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Transgenic Animal Core Facility (TACF) serves as a central molecular biology resource for the conception and execution of new projects and provides resources to help offset the high costs of developing genetically engineered mice. The objective of the TACF is to provide unique research tools to the staff at West Virginia University, the Blanchette Rockefeller Neuroscience Institute and the National Institute of Occupational Safety and Health. The TACF currently offers transgenic production, chimera production, mouse line rederivation, mouse embryo cryopreservation and mouse embryo resuscitation. The TACF staff is available for education, assistance and consultation during all stages of project development and production.