Psychiatry Consultation Liaison Service Research

在整个NIH内部研究计划中，精神病学咨询联络服务成员和临床医生之间的临床互动允许在内科疾病患者的精神病学和心理社会研究领域进行独特的研究合作。在美国国立卫生研究院其他研究所参加研究试验的患者-受试者提供了无与伦比的机会来探索特定基因(例如单基因疾病)和特定疗法(例如肝炎中的干扰素α)在精神病学和神经发育中的作用。 PCLS神经心理学咨询于2008年10月启动。该服务已经进行了200多次神经心理评估。这些对医学疾病的神经认知表型的评估中有三分之二是NIMH与其他研究所(如NIAMS、NHGRI、NIAID)合作研究的结果。NHLBI、NINDS和其他。 我们在儿科急诊室对患有内科疾病的儿童进行自杀筛查工具的重新验证和自杀筛查工作进展顺利，所有三个地点(华盛顿特区、波士顿、马萨诸塞州和俄亥俄州哥伦布市)的登记工作都在进行中。 与心理健康和儿科肿瘤学临床医生的合作导致了关于儿科肿瘤学护理的精神病学和心理社会方面的强有力的研究计划的发展，最终产生了一本关于儿科肿瘤学护理的心理和精神病学方面的手册(见下文)。有几个方案正处于数据收集阶段，包括评估儿科内科疾病人群中的痛苦体温计，以及“独生子女”的特征。 临床主任办公室人类受试者保护股(HSPU)的临床研究倡导者已经制作了知情同意培训视频，将在来年试行。此外，他们还将在来年介绍他们在实施评估和保护研究中易受伤害对象的标准化进程方面的经验。 在过去的一年里，这项研究已经产生了以下列出的多个出版物、几张海报和十几个国家演示文稿。

The clinical interactions between members of the Psychiatric Consultation Liaison Service and clinicians throughout the NIH intramural research program allows for unique research collaborations in the areas of psychiatric and psychosocial research in the medically ill. Patient-subjects enrolled in research trials in other Institutes at the NIH offer unparalleled opportunities to explore the roles of specific genes (e.g., monogenic diseases) and specific therapies (e.g., interferon alpha in hepatitis) in psychiatry and neurodevelopment. PCLS Neuropsychology Consultations were initiated in October 2008. The service has performed over 200 neuropsychological evaluations. Two-thirds of these evaluations for neurocognitive phenotyping of medical disorders have been as a result of research collaborations between NIMH and other Institutes such as NIAMS, NHGRI, NIAID. NHLBI, NINDS and others. Our suicide screen tool revalidation and suicide screening of medically ill children in a pediatric emergency room is well-underway with enrollment at all three sites (Washington, D.C., Boston, Massachusetts, and Columbus, Ohio) proceeding. Collaboration with mental health and pediatric oncology clinicians has led to the development of a robust research program on psychiatric and psychosocial aspects of pediatric oncology care, culminating in the production of a handbook on psychological and psychiatric aspects of pediatric oncology care (see below). Several protocols are in data-collection phase including evaluation of a distress thermometer in pediatric medically ill populations and characterization of "lone" parenting. The Clinical Research Advocates of the Human Subjects Protections Unit (HSPU), in the Office of the Clinical Director, have produced an informed consent training video that will be piloted in the coming year. In addition, they will presenting this coming year on their experiences regarding implementing processes to standardize the evaluation and protection of vulnerable subjects in research. This research has resulted in multiple publications listed below, several posters, and more than a dozen national presentations in the past year.