Gastrointesinal Stem Cell Meeting

描述（由申请人提供）：本申请请求支持2012年8月27-28日在伊利诺伊州芝加哥举行的2012年阿加弗雷斯顿胃肠干细胞会议。本次会议旨在汇集对胃肠道干细胞广泛主题感兴趣的研究人员，以研究和讨论器官干细胞内的共同主题，并确定器官特异性干细胞的独特特性。会议还试图研究正常粘膜干细胞和与胃肠道癌症相关的干细胞之间的差异的开创性问题。本次会议的一个中心目标是激发对干细胞的组织特异性的讨论，以及关于干细胞群体的起源、维持、再生和退化的统一概念的存在。为此，会议分为三组演讲机会：1）邀请代表干细胞生物学和功能的不同观点的专家演讲者，2）从提交的摘要中选择的初级教师和学员的演讲，3）基于摘要提交的海报演示。组织的演讲者会议涵盖了一般干细胞特性，肠干细胞，肝干细胞，胰腺干细胞和胃食管干细胞的主题。该方案的组织目的是促进一般性讨论，演讲时间限制在15分钟，讨论时间为10分钟，公开海报时间为2小时。由于这次会议的一个主要目标是将初级调查员和受训人员与该领域的专家聚集在一起，我们在本提案中寻求获得旅行津贴方面的支持，以便为25名受训人员和15名初级教员出席这次会议提供资金。) 公共卫生相关性：最近在胃肠道干细胞研究方面的研究已经对胃肠道组织如何组装、对损伤的反应以及癌症干细胞与正常祖细胞的不同有了新的认识。该提案旨在为初级教师和学员出席2012年阿加弗雷斯顿会议GI干细胞，在该领域的专家讨论干细胞研究的关键问题的主要聚会的资金。

DESCRIPTION (provided by applicant): This application requests support for the 2012 AGA Freston Conference on Gastrointestinal Stem Cells in Chicago, IL on August 27-28, 2012. This conference seeks to bring together investigators with interest in the broad topic of Gastrointestinal Stem Cells to examine and discuss the common themes within organ-based stem cells as well as identify unique properties of organ-specific stem cells. The conference also seeks to examine the seminal question of the differences between normal mucosal stem cells and stem cells associated with GI cancers. A central goal of this conference is to stimulate discussion of the tissue specific properties of stem cells and the existence of unifying concepts about the origin, maintenance, regeneration and degeneration of stem cell populations. To that end the conference is organized into three groups of presentation opportunities: 1) invited expert speakers representing divergent views of stem cell biology and function, 2) presentations from junior faculty and trainees selected from the submitted abstracts and 3) poster presentations based on abstract submissions. Speaker sessions are organized cover the topics of general stem cell properties, intestinal stem cells, liver stem cells, pancreas stem cells and gastroesophageal stem cells. The program has been organized to promote general discussion with presentations limited to 15 minutes with 10 minutes of discussion and a two-hour open poster session. Since a major goal of this meeting is to bring junior investigators and trainees together with experts in the field, we seek in this proposal to obtain support for travel stipends that would fund the attendance of 25 trainees and 15 junior faculty members at this meeting. ) PUBLIC HEALTH RELEVANCE: Recent studies in gastrointestinal stem cell research have led to new insights into how GI tissues are assembled, respond to injury and how cancer stem cells differ from normal progenitor cells. This proposal seeks funding for junior faculty and trainee attendance at the 2012 AGA Freston Conference on GI Stem Cells, a major gathering of experts in the field to discuss key issues in stem cell research.