GLYCOSCIENCE SKILLS DEVELOPMENT CORE

血糖科学技能核心C，Midura)这种NHLBI聚乙二醇化应用需要建立跨学科的研究 在第一年结束前为最多五名科学家参与者提供血糖科学技能。我们将实现这一技能 开发有4个目标：1)教学指导--PEG参与者将参加一个2小时的讲座/期刊 每隔一周去一次俱乐部。这2小时将被细分为45分钟的由教职员工主持的讲座。 描述选定的糖科学主题背后的原则，包括 糖胺多糖和蛋白多糖的研究。在这场教师讲座之后，将有一个60分钟的日记俱乐部 由教职员工协助，3-4名学生将发表一篇10-15分钟的摘要 从预先选定的糖科学研究重要文章列表中挑选文章。整个课程将是 在两年内完成，每两年重复一次。2)共享资源核心培训--聚乙二醇 预计学员将安排与共享资源核心(“资源核心”)的培训时间。 他们将观察资源核心人员运行专门的分析和技术，然后他们将运行 这些相同的测试都是在资源核心人员的指导下亲手完成的。每位参与者 将为他们将提供的所有共享资源核心技术提供详细的分步指导手册 在完成培训课程后继续进行培训。3)正式的研讨会培训--参加培训的人员将参加 格鲁吉亚大学复合碳水化合物研究中心(CCRC)课程(格鲁吉亚雅典) 在那里，他们将在每年8月和9月举行的正式研讨会上获得动手培训。(4)访问学者 项目-聚乙二醇组的参与者将在克利夫兰大学邀请并主持一个访问血糖科学学者项目。 每年就诊3次。其中一个空缺将由邀请加州大学中国研究中心的教职员工来填补。 在两天半的时间里去看克利夫兰诊所。另外两个名额将由世界知名的 来自外部大学的教职员工将在2.5天内访问克利夫兰诊所，与聚乙二醇组会面 参与者和每年一次的PEG教职员工。此外还有3名核心C级访问学者。核心A将 每年邀请一名外部咨询委员会成员，该成员还将向专家小组与会者介绍一次研讨会。 相关性(请参阅说明)： 这一聚乙二醇应用程序将转化糖科学的发现，以加强现有的跨学科研究 克利夫兰诊所的心、肺和血液研究能力。下一代调查人员将 为了掌握这些新兴的研究领域，需要进行血糖科学方面的教学和实践培训。这个 糖科学技能发展核心是传播此类糖学知识的关键。

Glycoscience Skills Core C, Midura) This NHLBI PEG application requires building interdisciplinary research skills in glycosciences for up to five scientist participants by the end of year 1. We will achieve this skill development with 4 objectives: 1) Didactic instruction - PEG participants will attend a 2 h lecture/journal club every other week. These 2 h will be sub-divided into a 45 minute faculty member-mediated lecture delineating the principles behind selected glycoscience topics, including the technologies used in glycosaminoglycan and proteoglycan research. This faculty lecture will be followed by a 60 min journal club facilitated by the faculty member whereby 3-4 students will present a 10-15 min summary of one published article from a pre-selected list of important articles in glycoscience research. The entire curriculum will be completed over a two year period and will repeat every 2 years. 2) Shared Resources Core training - PEG participants will be expected to schedule training time with the Shared Resources Core ("Resources Core"). They wilt observe Resources Core personnel running speciflc assays & technologies, and then they will run these same tests with their own hands under the guidance of Resources Core personnel. Each participant will be given a detailed step-by-step instrucflon manual for all shared resource core techniques that they will keep after completion of their training sessions. 3) Formal workshop training - PEG participants will attend courses at the Complex Carbohydrate Research Center (CCRC), University of Georgia (Athens, Georgia) where they will obtain hands on training in formal workshops held every August & Sept. (4) Visiting scholar program - PEG participants will invite & host a Visiting Glycosciences Scholar program at the Cleveland Clinic 3 times per year. One of these slots will be filled by inviting faculty members from the CCRC at UGA to visit the Cleveland Clinic over a 2.5 day period. The other 2 slots will be filled by inviting world renowned faculty from outside universities to visit the Cleveland Clinic over a 2.5 day period to meet with PEG participants and PEG faculty on an annual basis. In addition to the 3 Core C visiting scholars. Core A will invite annually an External Advisory Board member who will also present a seminar to PEG participants. RELEVANCE (See instmctions): This PEG application will translate glycoscience discoveries to strengthen existing interdisciplinary research capacities in heart, lung & blood research at the Cleveland Clinic. The next generation of investigators will need both didatic & hands on training in glycosciences in order to master these emerging fields of study. The Glycosciences Skills Development Core is critical for disseminating such glycoscience knowledge.