Interdisciplinary Training Program in Immunology

项目概要：这项培训补助金目前已进入第40个资助年度， 芝加哥大学免疫学培训项目的研究生。程序功能 在一个多样化的环境中，基础生物科学和医学院被整合在 同一部门在一个单一的校园在海德公园，芝加哥，IL。它体现在免疫学委员会， 一个跨学科和跨部门的学术单位，作为科学界， 免疫学研究生、博士后和大学教员。我们的培训计划的教师是 由34名杰出的培训师组成，他们因出色的研究和培训记录而被选中，他们的良好- 资助的实验室和他们在计划的各个方面的动态参与。他们形成了一个多样化的，年龄-和 一个性别平衡的小组，其研究涵盖了广泛的现代免疫学领域，包括 细胞和分子免疫学，生物化学，基因组学，系统生物学，微生物组研究，分子 工程学和人类免疫学，具有跨学科合作的良好记录。新的力量是 从最近招聘的五名国际公认的高级教师与专业知识， 免疫工程和免疫遗传学，以及三个初级教师与系统免疫学的专业知识， 粘膜免疫学和骨髓疾病。博士前学生通过课程接受高级培训 侧重于主要文献和实验设计的批判性分析，特别强调 计算技能、严谨性和可重复性，以及负责任的研究行为。综合 培训包括每周一次的系列研讨会、正在进行的工作论坛和期刊俱乐部，以及每年的 联合免疫学务虚会与其他顶级免疫学计划在中西部举行。职业发展是 通过MyChoice增强，这是一个机构计划，使学员能够进一步发展学术技能， 获得广泛的研究密集型职业道路，以及与芝加哥大学的合作伙伴关系 Polsky创业与创新中心。生物科学部提供强大的 机构支持，如持续的财政和行政支持，尖端技术的运作， 核心设施，如gnotobiotics，并实施重大举措，如Duchossois家庭 研究所，一个新的研究所，旨在利用微生物组的力量和人类免疫力 健康该计划在组织，领导， 目标和成果。这是全国最优秀、最具竞争力的培训项目之一， 正如我们的学员的高保留率和完成率所显示的那样（其中包括许多来自 少数民族背景），其令人印象深刻的出版率（平均每六个出版物， 培训生，包括许多第一作者的出版物在期刊上，如自然，免疫，细胞宿主和微生物， JEM和PNAS），以及他们在确保独立科学事业方面的成功。

PROJECT SUMMARY: This training grant, currently in its 40th year of funding, represents the primary support for graduate students in the Immunology Training Program at the University of Chicago. The program functions in a diverse environment where the basic biological sciences and the medical school are integrated within the same division in a single campus in Hyde Park, Chicago, IL. It is embodied by the Committee on Immunology, an interdisciplinary and interdepartmental academic unit that serves as the scientific community for immunology graduate students, postdocs, and faculty at the University. The faculty of our Training Program is composed of 34 distinguished trainers selected for their outstanding research and training records, their well- funded laboratories and their dynamic involvement in all aspects of the program. They form a diverse, age- and gender-balanced group whose research spans a broad spectrum of modern areas of immunology including cellular and molecular immunology, biochemistry, genomics, systems biology, microbiome studies, molecular engineering, and human immunology, with a proven record of interdisciplinary collaborations. New strength is drawn from the recent recruitment of five internationally recognized senior faculty with expertise in immunoengineering and immunogenetics, as well as three junior faculty with expertise in systems immunology, mucosal immunology, and myeloid disorders. Predoctoral students receive advanced training through courses focused on the critical analysis of primary literature and experimental design, with special emphasis on computational skills, rigor and reproducibility, and the responsible conduct of research. The comprehensive training includes a weekly Seminar Series, Work-in-Progress forum, and Journal Club, as well as an annual Joint Immunology Retreat held with other top immunology programs in the Midwest. Career development is enhanced through MyChoice, an institutional program enabling trainees to further develop academic skills and gain exposure to a broad array of research-intensive career paths, as well as a partnership with the UChicago Polsky Center for Entrepreneurship and Innovation. The Biological Sciences Division provides strong institutional support, as shown by sustained financial and administrative support, the operation of cutting-edge core facilities such as gnotobiotics, and the implementation of major initiatives such as the Duchossois Family Institute, a new research institute aimed at harnessing the power of the microbiome and immunity for human health. The Program is continuously and rigorously evaluated with respect to organization, leadership, objectives and outcomes. This is one of the most outstanding and competitive training programs in the country, as shown by the high retention and completion rates of our trainees (which include many students from underrepresented minority backgrounds), their impressive publication rate (average of six publications per trainee, including many first-author publications in journals such as Nature, Immunity, Cell Host & Microbe, JEM, and PNAS), and their success in securing independent scientific careers.