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中文摘要
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MVAHCS ACUP要求购买低温灭菌装置, Getinge Sterizone VP4。该装置使用过氧化氢蒸汽 和臭氧来消毒设备, 灭菌剂或传统高压灭菌器的高温和高压,或不 通过这些方法有效地消毒。这个特殊的单位也是唯一一个它的 一种已经获得FDA批准的内窥镜灭菌产品, 类似于ACUP中需要灭菌的器械,例如植入式 电子传输器、神经插管或窄规格血管收缩器 塑料做的。 许多涉及动物的研究项目需要手术植入或使用 这种敏感的设备。我们的项目包括: 大脑/机器接口,可能导致假肢;评估的影响, 对心血管疾病损害的心脏的各种治疗;揭示作用 饮食在神经元炎症和神经退行性疾病中的作用; 各种神经递质对肥胖和肥胖相关疾病影响。
英文摘要
The MVAHCS ACUP requests the purchase of a low temperature sterilization unit , the Getinge Sterizone VP4. The unit uses a combination of hydrogen peroxide vapor and ozone to sterilize equipment that either cannot withstand immersive liquid sterilants or the high heat and pressure of a traditional autoclave, or are not effectively sterilized by these methods. This particular unit is also the only one of its kind to have received FDA approval for sterilization of endoscopes, a product similar to the devices that require sterilization in the ACUP, such as implantable electronic transmitters, neural cannulae, or narrow gauge vascular constrictors made of plastic. Many research projects involving animals require the surgical implantation or use of such sensitive devices. Such projects within our program include: improving the brain/machine interface that could lead to artificial limbs; evaluating the effects of various therapies on hearts damaged by cardiovascular disease; uncovering the role of diet in neuronal inflammation and neurodegenerative disease; and evaluating the impact of various neurotransmitters on obesity and obesity-related disease.
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