DEVELOPMENT OF MEDICAL COUNTERMEASURES TO MITIGATE AND/OR TREAT RADIATION-INDUCED LUNG INJURY AFTER A RADIOLOGICAL/NUCLEAR INCIDENT)
DEVELOPMENT OF MEDICAL COUNTERMEASURES TO MITIGATE AND/OR TREAT RADIATION-INDUCED LUNG INJURY AFTER A RADIOLOGICAL/NUCLEAR INCIDENT)
制定医疗对策以减轻和/或治疗放射/核事件后辐射引起的肺损伤）
批准号：
9476857
负责人：
ANDREW NORRIS
金额：
$182.8万
依托单位：
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
项目状态：
已结题
起止时间：
2015-06-01 至 2018-05-31
关键词：
Benefits and RisksBiological MarkersChemistryContractsCoupledDataDevelopmentDrug KineticsDrug usageExposure toGoalsHourInjuryIonizing radiationLeadLungMedicalMetabolismModelingMorbidity - disease rateNuclearNuclear RadiologyPharmaceutical PreparationsPharmacodynamicsPharmacology and ToxicologyRadiationRadiation exposureRadiology SpecialtyResearchResearch SupportTestingTherapeuticWorkanimal ruledesignefficacy studylung injurymodel developmentprogramsradiation mitigatorsubcutaneous
中文摘要
翻译
该合同将支持研究，以加速开发安全有效的医疗产品，以减轻和/或治疗放射或核事件电离辐射照射造成的肺损伤，从而减少可能影响生存的肺部相关发病率。目前，国家战略储备（SNS）中没有批准的治疗产品专门用于放射性肺损伤。
英文摘要
This contract will support research to accelerate the development of safe and effective medical products to mitigate and/or treat pulmonary injury arising from exposure to ionizing radiation from a radiological or nuclear incident, thereby leading to a reduction in lung-associated morbidities that can impact survival. Currently, there are no approved therapeutic products in the Strategic National Stockpile (SNS) to be used specifically for radiation-induced pulmonary injury.
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