Multiple Sclerosis: Does treatment reduce long-term disability progression?

多发性硬化症是一种影响超过20，000名澳大利亚人的疾病，并导致大多数患者严重残疾和社会混乱。这是一种持续数十年的疾病，这使得很难准确确定最佳治疗策略。我们建议使用一项登记研究，该研究已经跟踪了全球16，000多名MS患者，以检查哪些治疗策略在这些患者中提供了最高的获益/风险比，因为所观察到的疾病严重程度差异很大。

Multiple Sclerosis is an illness affecting more than 20,000 Australians, and causes significant disability and social disruption in most sufferers. It is an illness which progresses over decades, and this makes it difficult to accurately determine the best treatment strategies. We propose to use a registry that has followed more than 16,000 people with MS globally to examine which treatment strategies have provided the highest benefit/risk ratio in these patients, given the great variability of disease severity seen.