Training Program in Neuroendocrinology of Homeostasis

描述(由申请人提供)：这是辛辛那提大学医学院(UCCOM)更新其长期培训计划(T32 DK059803)的建议，该计划支持在能量平衡和下丘脑-垂体-肾上腺(HPA)应激轴调节的神经内分泌学方面的博士后和博士后培训，重点放在性别差异的作用上。培训拨款与UCCOM自我们最初提交以来多年来在神经科学研究，特别是神经内分泌学方面的巨大增长很好地契合并加强了这一点。培训计划的教员由来自不同部门的高素质和资金充足的研究人员组成，他们对新陈代谢和压力动态平衡有共同的兴趣，大多数教员位于最近翻新的UCCOM新陈代谢疾病研究所(MDI)的连续空间。我们培训结构的主要目的是使学生和研究员能够理解并将动态平衡原则应用于他们的研究，并提供一个鼓励学生和研究员探索涉及多个重点领域的研究的环境。特别是，我们希望让学生接触到广泛的先进技术，他们可以将这些技术纳入他们正在进行的和未来的研究中。对博士后和博士后实习生的培训包括课程作业、研讨会和期刊俱乐部，以及广泛的一对一指导，在各级都强调道德和负责任的研究行为。我们认为，我们在招聘、培训和安置高素质受训人员方面取得了出色的成绩，对任职人数不足的少数族裔受训人员尤其如此。对于这次续签申请，我们是 根据先前审查的建议，申请资助3名博士后学生和3名博士后实习生。博士前学生将通过他们的普通考试，并获得博士论文的支持，所有受训人员预计在2至3年内完成培训。

DESCRIPTION (provided by applicant): This is a proposal from the University of Cincinnati College of Medicine (UCCOM) to renew its long-standing training program (T32 DK059803) that supports predoctoral and postdoctoral training in the neuroendocrinology of energy balance and hypothalamo-pituitary-adrenal (HPA) stress axis regulation, with an emergent focus upon the role of sex differences. The training grant fits well with and enhances the tremendous growth in neuroscience research in general, and neuroendocrinology in particular, enjoyed by the UCCOM over the years since our original submission. The faculty of the training program consists of highly qualified and well-funded investigators from diverse departments with a common interest in metabolic and stress homeostasis, and most of the faculty are located in contiguous space at the recently renovated Metabolic Diseases Institute (MDI) of the UCCOM. The primary purpose of our training structure is to enable students and fellows to understand and apply principles of homeostasis to their research, and to provide an environment that encourages students and fellows to explore research that involves more than one of the focus areas. In particular, we want to expose students to a broad array of advanced techniques that they can be incorporated into their ongoing and future research. The training for both pre- and post-doctoral trainees includes a blend of coursework, seminars and journal clubs, and extensive one-on-one instruction, and at all levels there is an emphasis upon ethics and the responsible conduct of research. We believe that we have achieved an outstanding record of accomplishment in terms of recruiting, training and placing highly qualified trainees, and that thi is particularly true for under- represented minority trainees. For this renewal application, we are requesting funding for 3 pre- doctoral students and 3 post-doctoral trainees as recommended by prior reviews. The pre- doctoral students will have passed their general exams and be supported for their doctoral thesis, and all trainees are anticipated to complete their training within 2 to 3 years.