Addressing High Risk Alcohol Use Amongst Injury Patients in an Emergency Department in Tanzania

 描述（由申请人提供）：每年，全球有180万人死于酒精。在低收入和中等收入国家，酒精的使用正在迅速增加，在这些国家，酒精价格低廉，容易获得，监管不力，而且用于安全饮酒行为的资源很少。像许多其他资源有限的环境一样，坦桑尼亚基利曼哈罗地区几乎没有治疗设施或戒毒从业人员。这个职业发展奖将允许文化适应，验证和酒精使用的简短谈判面试的试点测试。为此，该项目将1）描述坦桑尼亚目前对酒精使用的认识和看法，2）根据坦桑尼亚的情况调整循证干预措施，3）在准备大型scae试验时试行这种干预措施。干预，一个简短的谈判面试，动机面试框架的基础上，已被证明是有效的，在美国，但尚未适应或实施在非洲的背景下。鉴于我10年的临床和研究全球健康经验，我是唯一有资格领导这个项目的人。我致力于全球健康研究事业，融入了基利曼哈罗基督教医疗中心社区，并进行了基本的酒精流行病学研究，为这个奖项做准备。为了成为一名专注于解决酒精使用问题的独立研究人员，我正在寻求混合方法研究，动机访谈，全球临床试验和负责任的研究行为的进一步技能。这一提议不仅为我提供了非洲所需的独特的研究专业知识组合，而且为遏制非洲酒精使用的影响奠定了开创性研究的基础。

 DESCRIPTION (provided by applicant): Annually, there are 1.8 million global deaths due to alcohol. Alcohol use is rapidly increasing in low and middle-income countries, where it is inexpensive, readily available, poorly regulated, and there are few resources devoted to safe alcohol use behavior. Like many other limited resource settings, there are few treatment facilities or addiction practitioners in the Kilimanjaro region of Tanzania. This career development award will allow for the cultural adaptation, validation, and pilot testing of a brief negotiational interview for alcohol use. To do so, the project will 1) describe the current knowledge and perceptions about alcohol use in Tanzania, 2) adapt an evidence-based intervention to the Tanzanian setting and, 3) pilot this intervention in preparation of a large-scae trial. The intervention, a brief negotiational interview, based on a motivational interviewing framework, has proven effective in the US but has not been adapted or implemented in an African context. I am uniquely qualified to lead this project given my 10 years of clinical and research global health experience. I am dedicated to a global health research career, am integrated into the Kilimanjaro Christian Medical Center community, and have conducted the basic alcohol epidemiology research in preparation for this award. To become an independent researcher focusing on addressing alcohol use, I am seeking further skills in mixed methods research, motivational interviewing, global clinical trials, and the responsible conduct of research. This proposal not only provides me with a unique combination of research expertise that are needed in Africa, but also lays a foundation for groundbreaking research to curb the impact of alcohol use in Africa.