Monitoring and Stabilizing Behavioral Rhythms to Improve Mental Health

摘要：HealthRhythms，Inc. 大量证据支持这样一种观点，即行为常规(或社交节律)的规律性被打乱会导致 通过对内源性昼夜节律的影响而出现精神症状和全面发作，反之亦然 这种稳定的社交习惯可以防止新的情绪发作。基于我们的信念，监控、评估和 我们发现，增加行为节律的规律性对改善心理健康具有广泛的适用性 HealthRhythms，Inc.(www.achthhythms.com)，目标是使用移动技术增加心理健康层 关爱所有的医疗保健。我们的产品模式利用了智能手机的无处不在和亲密性，以及它们的能力 行为的感觉参数，代表心理健康的关键指标，全天候在用户的自然状态下捕获 环境，而不是迄今以精神卫生保健为特征的零星的临床测量。该产品 我们设想最终将有三个支柱：节奏感知、节奏趋势和节奏稳定。前两个 这些支柱已经开发出来，我们产品的数千个许可证已经售出。建立在我们的 到目前为止的成就，这份SBIR第二阶段直接建议书在三个方面扩展了我们的工作：1)进一步验证我们现有的 技术，2)开发我们的下一阶段技术，3)扩展和改进我们的预测模型和 展示了我们技术的成本效益。具体目标是：目标1：加强我们的节奏趋势 通过深入检查和分析来自3,000多名已与我们产品合作的患者的数据而实现的功能 已经部署好了。目标2：开发我们技术的节律稳定支柱。目标3：扩展的性质 我们的预测模型中包含的数据，并展示了它们的实用性。

Abstract: HealthRhythms, Inc. Substantial evidence supports the idea that disruptions in the regularity of behavioral routines (or ‘social rhythms’) can lead to the onset of psychiatric symptoms and full blown episodes via their impact on endogenous circadian rhythms and, conversely that stable social routines protect against new mood episodes. Based on our conviction that monitoring, evaluating, and increasing the regularity of behavioral rhythms has broad applicability for improving mental health, we established HealthRhythms, Inc. (www.healthrhythms.com) with the goal of using mobile technology to add the layer of mental health care to all of healthcare. Our product model capitalizes on the ubiquity and intimacy of smartphones and their capacity to sense parameters of behavior that represent key indicators of mental health on a 24/7 basis captured in the user’s natural environment, opposed to the sporadic, in-clinic measurement that has characterized mental healthcare to date. The product we envision will ultimately have three pillars: Rhythm Sensing, Rhythm Trending, and Rhythm Stabilization. The first two of these pillars have been developed and thousands of licenses for our product have already been sold. Building on our accomplishments to date, this SBIR Phase II Direct proposal extends our work in three ways: 1) further validating our existing technology, 2) developing the next stage of our technology and 3) expanding and improving our prediction models and demonstrating the cost-effectiveness of our technology. The Specific Aims are: Aim 1: Enhance our Rhythm Trending capabilities through intensive examination and analysis of data from the 3,000+ patients with whom our product has already been deployed. Aim 2: Develop the envisioned Rhythm Stabilization pillar of our technology. Aim 3: Expand the nature of the data included in our prediction models and demonstrate their utility.