Tool Core- Boutros

工具优化核心：摘要(项目描述) 除了数据集，Bridge2AI的数据生成项目(DGPS)将创建一套丰富的软件方法和 工具。工具优化核心(TOC)将成为全国和多国的算法和方法中心- 逻辑创新、对标、规范、优化、传播。我们渴望成为一个公地 为广泛而多样的利益相关者提供服务：算法开发人员和用户、公民科学家、REG- 监管机构和公众。 在这一总体使命下，我们的目标是结合每个利益相关者的具体需求，以及合并 专业知识、创新和传播，在更广泛的Bridge2AI计划中实现工具优化。我们的 工具优化核心包括五个具体目标。首先，我们将支持工具泛化。目标为本课程将 作为基准测试、软件开发和用户界面(UI)开发方面的卓越中心 以及提供资源以支持关键的现有工具和由数据生成项目生成的工具 (DGPS)。其次，我们将协调Bridge2AI内部和外部的工具开发。目标为本课程将协调 与NIH资助的其他财团合作的DGPS基准、标准设置和接口开发 和主动性。第三，我们将对工具进行基准和优化。目标为本课程将每季度确定、计划和执行 潘-Bridge2AI众包基准测试练习，以确定和量化最佳实践，同时与 DGPS上的各种算法。第四，我们将发现和填补工具开发、优化和 泛化。TOC将创建跨DGPS工具开发和优化模块的工作组 确定差距并随后协调黄金标准数据集的创建和工具优化 空格。第五，我们将传播工具开发和优化方面的最佳做法。目标为本课程将创建一个 标准化注册中心，用于与这些可用资源共享工具、数据集和基准测试结果 通过编程和可视化界面。 这些努力将通过TOC与其他桥梁协调中心核心的协调来实现， 特别是包括标准核心和技能与劳动力发展核心。成功的执行将 允许TOC为DGPS提供全面建议，在和 超越Bridge2AI，开发Bridge2AI范围的基准测试，协调Bridge2AI中的工具开发，以及 开发和主办有关Bridge2AI的研讨会和系统培训材料。目标为本课程所作的努力将会支持 不断改进和发展工具，对科学界产生持久影响。

TOOL OPTIMIZATION CORE: ABSTRACT (PROJECT DESCRIPTION) Beyond datasets, Bridge2AI’s Data Generation Projects (DGPs) will create a rich set of software methods and tools. The Tool Optimization Core (TOC) will be a national and multi-national hub for algorithmic and methodo- logic innovation, benchmarking, standardization, optimization, and dissemination. We aspire to be a Commons that services a broad and diverse range of stakeholders: algorithm developers and users, citizen scientists, reg- ulatory bodies, and members of the public. With this overarching mission, our TOC aims to incorporate each stakeholders’ specific needs as well as merge expertise, innovation, and dissemination to enable tool optimization across the broader Bridge2AI initiative. Our Tool Optimization Core comprises five Specific Aims. First, we will support tool generalization. The TOC will serve as a Center of Excellence in benchmarking, software development, and user interface (UI) development as well as provide resources to support critical existing tools and tools generated by data generating projects (DGPs). Second, we will coordinate tool development within and beyond Bridge2AI. The TOC will coordinate benchmarking, standards-setting, and interface development for DGPs working with other NIH-funded consortia and initiatives. Third, we will benchmark and optimize tools. The TOC will identify, plan, and execute quarterly pan-Bridge2AI crowdsourced benchmarking exercises to identify and quantify best-practices while working with DGPs on a wide range of algorithms. Fourth, we will identify and fill gaps in tool development, optimization, and generalization. The TOC will create working groups across the DGPs Tool Development & Optimization Modules to identify gaps and subsequently coordinate creation of gold standard datasets and tool optimization in these spaces. Fifth, we will disseminate best practices in tool development and optimization. The TOC will create a standardized registry for sharing of tools, datasets, and benchmarking results with these resources available through programmatic and visual interfaces. These efforts will be achieved through coordination of the TOC with other BRIDGE Coordination Center Cores, particularly including the Standards Core and Skills & Workforce Development Core. Successful execution will allow the TOC to comprehensively advise DGPs, create open and coordinated tool development within and beyond Bridge2AI, develop Bridge2AI-wide benchmarking, harmonize tool development across Bridge2AI, and develop and host workshops and systematic training materials on Bridge2AI. The efforts of the TOC will support continual tool refinement and development with lasting impact for the scientific community.