A Feasibility Study to Test the REST Tracker System for Use in Maternal Care to Improve Outcomes by Early Detection of Obstructive Sleep Apnea

摘要 妊娠期间阻塞性睡眠呼吸暂停(OSA)与妊娠风险增加相关 糖尿病、高血压、先兆子痫和子痫，导致孕产妇和新生儿发病率和 死亡率。此外，OSA会增加怀孕后患慢性心血管疾病的风险，增加 孕期检测和处理的风险。研究表明，糖尿病的流行 随着孕妇体重指数(BMI)的上升，OSA在怀孕期间会增加。持续评估是 然而，由于在整个妊娠过程中发生阻塞性睡眠呼吸暂停综合征的风险增加是必要的，但这并不是 目前，这是产前护理的一种标准做法。多导睡眠图或家庭睡眠对阻塞性睡眠呼吸暂停综合征的连续筛查 呼吸暂停测试是不切实际的，而且在经济上是令人望而却步的。因此，需要改进的工具来提供 在怀孕期间简单而准确地检测OSA以防止潜在的后果。睡眠专家 没有提供具体的方法来帮助产科医生解决OSA问题，在我们的 孕产妇健康管理。我们的建议旨在解决这一差距。 REST科技公司过去一直参与提供支持临床睡眠医学的服务 二十年了。现在，使用远程患者监控、最先进的信号处理和数据还原 技术REST技术REST跟踪器系统可以改善产妇健康。此外，除了 在怀孕期间检测OSA，OSA治疗管理本身可以使用相同的优化 监控方法。妊娠期间的渐进性生理变化使其成为老年人的理想人群 REST Tracker系统开发，因为该方法可推广到其他高危人群。这笔赠款 重点展示实施远程患者监控以全程跟踪孕妇的可行性 她们的怀孕对病人来说是一种简单的方式，但却产生了与睡眠和睡眠有关的关键数据 生理学。为该项目组建的团队拥有丰富的临床经验，并计划为 超越母体监测的睡眠医学实践加强远程医疗临床的探讨 小路。

Abstract Obstructive sleep apnea (OSA) during pregnancy is associated with increased risk of developing gestational diabetes, hypertension, preeclampsia, and eclampsia, contributing to maternal and neonatal morbidity and mortality. Furthermore, OSA increases risk of chronic cardiovascular disease, well beyond pregnancy, raising the stakes for detection and management during pregnancy. Research studies suggest that the prevalence of OSA increases during pregnancy, as the maternal body mass index (BMI) rises. Continuous evaluation is necessary as the risk of developing OSA increases throughout the course of the pregnancy however this is not currently a standard practice in prenatal care. Serial screenings for OSA with polysomnograms or home sleep apnea tests are impractical and financially prohibitive. Thus, the need arises for improved tools that provides simple and accurate detection of OSA during pregnancy to prevent potential consequences. Sleep specialists have not provided a specific approach to assist obstetricians addressing OSA concern, leaving a gap in our maternal health management. Our proposal seeks to address this gap. REST Technologies has been involved with providing services to support clinical sleep medicine for the past twenty years. Now, using remote patient monitoring, state-of-the-art signal processing, and data reduction techniques REST Technologies REST Tracker system can improve maternal health. Additionally, beyond the detection of OSA during pregnancy, OSA treatment management itself can be optimized using this same monitoring approach. The progressive physiologic changes in pregnancy make it an ideal population for the REST Tracker system development, as the approach is generalizable to other at-risk populations. This grant focuses on demonstrating feasibility to perform Remote Patient Monitoring to track pregnant patients throughout their pregnancy is a fashion that is simple for the patient yet yielding critical data that relates to sleep and sleep physiology. The team assembled for this project have vast clinical experience and plan to bring innovative approaches to the practice of sleep medicine beyond maternal monitoring to enhance Telemedicine clinical pathways.