National Research Service Award-Medical Scientist

华盛顿大学圣路易斯分校的华盛顿大学医学科学家培训计划于#年建立。 1969年，自1970年以来一直由美国国立卫生研究院资助。它已经培养了658名医学博士，比任何一个项目都多 这个国家。自该计划成立以来，我们的主要目标是识别、培训和指导不同的 一群女性和男性，他们将成为生物医学研究、病人护理和医学教育的领导者。到那时候 最后，我们设计了一条灵活的、个性化的培训路径，强调临床和研究的结合 训练。该大学对该计划的重大承诺不仅体现在提供68%(860万美元) 2018财年)的MSTP总预算，还在调整课程和政策以适应独特的 医学博士研究生培养要求。该T32的任命通常是在培训的前3年进行的。我们是 能够通过大学和其他资金将赠款的44个培训名额中的每一个都利用4.4倍，这使得 美国将支持现有的192名学生。为了选择要在该计划中进行培训的个人，我们主要关注 学术成就、研究经验和对研究事业的承诺。学生们通常在 生物学和生物医学科学部，一个由11个博士项目组成的跨大学联盟，但有重要的 在其他学术单位进行数字培训，包括生物医学工程。这项提案的156名培训教职员工是 在这些学术单位的总人口中，有570多名终身教职教师。有政策来选择教职员工 参加研究生培训，每5年对培训师资进行一次审查。我们的节目很受欢迎 与华盛顿大学的其他项目进行互动，以培训内科科学家 博士学位，即我们临床住院医师和研究员计划中的医生-科学家培训计划(PSTP)。学生 流失率很低，在过去10年里大幅下降。Time to Degree稳定在8.0年，并且是 低于全国平均水平。结果数据显示，在完成研究生培训的人中，78% 受雇于学术机构、研究机构、联邦机构以及生物技术或制药公司。许多 有来自美国国立卫生研究院或其他来源的研究支持，有些人在其他医学博士项目中担任领导角色。 虽然我们的项目已经有了很长的成功历史，但我们认识到我们的学员未来将面临的挑战 在从事基础研究和转化性研究的内科科学家的职业生涯中取得成功。帮助他们达到 最高级别的成功，我们未来5年的目标包括：1)为学员提供学术课程， 将基础科学与临床医学相结合；2)为我们的实习生提供新的职业指导计划， 以成功的内科科学家为特色；3)建立在现有计划的基础上，以增强同志情谊并灌输信心 医生-科学家途径是可行的，也是值得的；4)与我们的PSTP同事合作，进一步加强 我们的学生成功的可能性；5)与我们的机构利益相关者合作，在没有 牺牲必要的严谨性，并在我们最近成功招聘到一批将成为 受过良好的培训，成为发现和应用开创性研究和创新患者护理的领导者。

The Washington University Medical Scientist Training Program at Washington University in St. Louis was established in 1969, and has been continuously funded by the NIH since 1970. It has trained 658 MD-PhDs, more than any program in the nation. As it has been since the program's founding, our primary goal is to identify, train, and mentor a diverse group of women and men who will become leaders biomedical research, patient care, and medical education. To that end, we have designed a flexible, individualized training pathway that emphasizes the integration of clinical and research training. The University's substantial commitment to the program is evident not only in providing 68% ($8.6 million in FY2018) of the total MSTP budget, but also in tailoring the curriculum and policies to accommodate the unique requirements of MD-PhD training. Appointments to this T32 are typically made for the first 3 years of training. We are able to leverage each of the grant’s 44 training slots by a factor of 4.4 through university and other funds, which allows us to support a current population of 192 students. To select individuals to train in the program, we focus primarily on academic achievement, research experience, and a commitment to a research career. Students typically train in the Division of Biology and Biomedical Sciences, a trans-university consortium of 11 doctoral programs, but a significant number train in other academic units, including Biomedical Engineering. The 156 training faculty for this proposal are out of a total population in these academic units of over 570 tenure-track faculty. Policies are in place to select faculty for participation in graduate training, and training faculty are reviewed every 5 years. Our program enjoys strong interactions with other programs at Washington University for training of physician-scientists after they receive their doctorates, i.e., Physician-Scientist Training Programs (PSTPs) in our clinical residency and fellowship programs. Student attrition is low and has declined significantly over the past 10 years. Time to degree has stabilized at 8.0 years, and is lower than the national average. Outcomes data shows that 78% of those that have completed postgraduate training are employed by academic institutions, research institutes, federal agencies, and biotech or pharmaceutical firms. Many have research support from the NIH or other sources, and some have leadership roles in other MD-PhD programs. While our program has had a long history of success, we are cognizant of the future challenges facing our trainees to achieve success in careers as physician-scientists involved in basic and translational research. To help them reach the highest levels of success, our goals for the next 5 years include: 1) Providing our trainees with academic programs that integrate basic science with clinical medicine; 2) Providing our trainees with a new career mentorship program that features successful physician-scientists; 3) Build on existing programs to enhance camaraderie and instill confidence that the physician-scientist pathway is viable and worthwhile; 4) Working with our PSTP colleagues to further enhance the likelihood of success of our students; 5) Working with our institutional stakeholders to reduce time to degree without sacrificing necessary rigor, and 6) Building on our recent success in recruiting a diverse cohort of individuals who will be well trained to be leaders in the discovery and application of ground-breaking research and innovative patient care.