Health Promotion and Disease Prevention Research Center

摘要 尽管越来越多的循证癌症预防和控制干预措施和战略 减少癌症负担，但大多数在当地社区并未得到很好的采用。埃默里CPCRN将增加 将癌症和HPV疫苗证据转化为当地社区。更广泛地使用有效的 干预措施可以显著降低癌症发病率和死亡率。Emory CPCRN有6个相互关联的 目标和意愿：目标1.维护和加强埃默里中心的基础设施，以支持和加强 癌症预防控制能力建设和实施科学研究与实践 埃默里和格鲁吉亚各地的农村社区；目标2.培养和加强与 社区、公共卫生机构、社区组织以及癌症控制研究和 建立实践网络，促进以社区为基础的参与式方法来预防癌症和减少 健康差距；目标3.开展国家和地方培训，建设通过和执行方面的能力 与我们的西南GA合作伙伴和地区性癌症联盟合作，采用循证方法； 目的4.使用P3(实践、提供者和患者水平)模型评估与HPV疫苗接种相关的因素 通过在佐治亚州西南部的定性研究告知干预发展情况；目标5a。评估多个- HPV疫苗小额赠款和技术援助实施策略的层级干预 在佐治亚州西南部的临床和社区组织中发起和完成系列活动；评估 使用综合框架的执行成果和与执行成功有关的因素 通过混合方法研究实施研究(CFIR)；和目标6.传播和翻译 向地方、地区和国家癌症控制研究人员和从业者提供研究成果。埃默里 CPCRN建议的目标将增强西南地区临床和社区组织的能力 格鲁吉亚和该州通过培训、研究和传播努力。我们将为 临床和社区组织采用循证干预的测试干预策略 用于提高HPV疫苗接种率。

ABSTRACT Despite the growing number of evidence-based cancer prevention and control interventions and strategies to reduce the burden of cancer, most are not well adopted in local communities. The Emory CPCRN will increase the translation of cancer and HPV vaccine evidence into local communities. Wider use of effective interventions can significantly reduce cancer morbidity and mortality. The Emory CPCRN has 6 inter-related aims and will: Aim 1. Maintain and strengthen the Emory CPCRN infrastructure to support and enhance capacity-building for cancer prevention and control and implementation science research and practice at Emory and in rural communities across Georgia; Aim 2. Cultivate and strengthen partnerships with communities, public health agencies, community-based organizations, and cancer control research and practice networks to promote community-based participatory approaches to preventing cancer and reducing health disparities; Aim 3. Conduct national and local trainings to build capacity on adoption and implementation of evidence-based approaches in collaboration with our Southwest GA partners and regional cancer coalitions; Aim 4. Assess factors related to HPV vaccination using the P3 (Practice, Provider, and Patient-Level) model to inform intervention development through a qualitative study in Southwest Georgia; Aim 5a. Evaluate a multi- level intervention employing implementation strategies of mini-grants and technical assistance on HPV vaccine series initiation and completion among clinical and community organizations in SW Georgia; 5b. Assess implementation outcomes and factors related to implementation success using the Consolidated Framework for Implementation Research (CFIR) through a mixed-methods study; and Aim 6. Disseminate and translate research findings to local, regional and national cancer control researchers and practitioners. The Emory CPCRN proposed aims will enhance the capacity of clinical and community organizations in Southwest Georgia and the state through training, research and dissemination efforts. We will contribute a model for testing intervention strategies for clinical and community organizations to adopt evidence-based interventions for increasing HPV vaccination rates.