Ga. Dept. of Agriculture - NARMS

NARMS-项目摘要/摘要 佐治亚州农业部(GDA)是负责监管 食品生产设施和零售场所。GDA实验室(实验室)是主要的服务 监管计划的实验室，并专注于化学和食品分析 微生物污染物。自2011年以来，GDA一直在寻求FDA的赠款和合作协议，以 提高和协调我们的国家监管和检测能力。通过这些赠款，实验室 获得国际标准化组织17025国际标准认证，使我们的监管机构能够 代表FDA履行合同工作。由于GDA是佐治亚州食品零售的监管机构 此外，该机构在乔治亚州各地都有检查员驻扎。这些 检查员接受培训，收集样本并将其送回我们的实验室进行测试，以支持 监管执法。 由于GDA已经为零售机构的样本采集指定了基础设施 和微生物分析实验室，这一奖项机会NARMS(国家抗菌素 阻力监测系统)应该很适合由GDA实施。佐治亚州 公共卫生部(GDPH)实验室目前获得了这笔赠款，但已与GDA联系 请求援助或接管援助，因为COVID 19大流行已成为他们的首要任务。 总而言之，GDA检查员将按照常规收集样本并将其发送到实验室 协议。该实验室将对资助中建议的目标生物的样本进行筛选 机会奖(FOA)。实验将利用项目协议中描述的方法，除了 通过批准和验证的ELISA法或PCR法进行筛查。具有典型特征的分离株将 需进一步检查确认或送FDA作进一步评估。根据需要，GDPH已同意 还协助对分离株进行全基因组测序，因为GDA目前还没有 能力，除了指导的方法和计划，直到完全建立。 该实验室已与其监管合作伙伴建立并展示了成功的关系 以及GDPH实验室，这应该表明它有能力实现这一目标。实验室也照例 每年对零售食品样本进行数千次微生物分析。如果获奖，GDA将被 能够增强和加强抗菌素耐药性监测数据。这反过来又可以是 用于向公共卫生利益攸关方通报耐药菌株的人群，以及如果当前政策和 这些做法足以保障消费者的整体安全。

NARMS - Project Summary/Abstract The Georgia Department of Agriculture (GDA) is the state agency responsible for regulation of food manufactured facilities and retail establishments. GDA Laboratories (Lab) are the primary servicing laboratories for the regulatory programs and are focused on food analysis for chemical and microbiological contaminants. Since 2011, GDA has pursued FDA grants and cooperative agreements to improve and harmonize our state regulatory and testing capability. Through these grants the Lab achieved accreditation to ISO 17025 international standards which allows our regulatory agencies to perform contractual work on behalf of FDA. Since GDA is Georgia’s regulatory authority over food retail establishments, the agency has inspectors positioned all throughout The State of Georgia. These inspectors are trained to collect samples and return them to our lab for testing that can support regulatory enforcement. Since GDA already has infrastructure designated for sample collection at retail establishments and the analysis of microorganisms by the Lab, this award opportunity NARMS (National Antimicrobial Resistance Monitory System) should make a good fit to be implemented by GDA. The Georgia Department of Public Health (GDPH) Laboratory is currently awarded this grant but has contacted GDA to request assistance or taking it over since the COVID 19 pandemic has become their top priority. In summary, GDA inspectors will collect the samples and send them to the Lab per routine protocols. The Lab will screen the samples for the target organisms suggested in the Funding Opportunity Award (FOA). The Lab will utilize methods described in the project protocol in addition to screening by approved and validated ELISA or PCR platforms. Isolates showing typical characteristics will be further examined and confirmed or sent to FDA for further evaluation. As needed, GDPH has agreed to also assist in in Whole Genome Sequencing of the isolates, since GDA does not currently have that ability, in addition to mentoring of the methods and program until fully established. The Lab has developed and demonstrated successful relationships with their regulatory partners and the GDPH Lab, which should indicate its ability to fulfill this objective. The Lab also routinely performs thousands of microbiological analyses on retail food samples annually. If awarded, GDA will be capable of enhancing and strengthening antimicrobial resistance surveillance data. This in turn can be used to inform public health stakeholders about populations of resistant strains and if current policy and practices are adequate for overall safety of consumers.