Molecular Biology in Clinical Oncology Workshop

项目总结：分子生物学在临床肿瘤学研讨会-CA057732 一系列细胞和分子生物学方法的发展和应用 基因结构和表达、细胞生长控制和恶性转化导致了 在癌症的诊断、治疗和预防方面取得显著进展。有越来越多的 在临床上有效应用这些知识的机会。内科医生-科学家尤其擅长 适合进行床边到床边以及床边到床边的癌症翻译研究。他们也是 促进护理提供者和基础研究人员之间沟通的天然桥梁。然而，许多人 临床肿瘤学研究员要么缺乏正式的科学指导，要么由于 临床培训的需求。 美国癌症研究协会(AACR)要求继续支持一项密集的研究- 自1992年7月开始运作的癌症分子生物学周夏季讲习班。这个 工作坊主要是为已达到团契培训水平的肿瘤学家设计的，并 有兴趣开始他们的研究事业。本研讨会的目标是向肿瘤学家介绍 分子和细胞生物学的基本概念和技术，并为它们配备科学的 他们需要的知识和职业建议，以将他们未来的职业生涯献给转化型癌症研究。这是 通过：1)由顶尖专家讲授分子生物学和MOST的基本概念 将这些概念转化为临床研究和实践的最新进展，如 他们自己的研究和实验设计；2)小组实验室会议，展示重要的 应用于基础分子生物学的实验技术；3)与世界一对一讨论的机会 该领域的领导者为参与者提供科学和职业发展建议，以及其他 非正式指导；4)编写赠款，介绍申请者撰写赠款和审查过程； 以及5)过去和现在的教职员工和与会者的在线社区，使用社交网络工具 促进科学信息和职业发展建议的交流。我们将评估该项目的成功 研讨会，以实现其规定的目标，包括使用计划评估，教师评估，和实习生 输入，并使用这些信息来不断改进研讨会。

Project Summary: Molecular Biology in Clinical Oncology Workshop – CA057732 The development and application of a range of cellular and molecular biological approaches to the study of gene structure and expression, cellular growth control, and malignant transformation have resulted in remarkable advances in the diagnosis, treatment, and prevention of cancer. There are increasing numbers of opportunities for effective application of this knowledge in the clinic. Physician-scientists are especially well suited to conduct bench to bedside, as well as bedside to bench, translational cancer research. They are also the natural bridges to foster communication between care providers and basic researchers. However, many clinical oncology fellows either lack formal scientific instruction or are removed from it for years due to the demands of clinical training. The American Association for Cancer Research (AACR) requests continuation of support for an intensive one- week summer Workshop on the molecular biology of cancer that has been in operation since July 1992. The Workshop is primarily designed for oncologists who have reached the fellowship training level and are interested in launching their research careers. The goals of this Workshop are to introduce oncologists to the essential concepts and techniques of molecular and cellular biology, and to equip them with the scientific knowledge and career advice they need to devote their future careers to translational cancer research. This is accomplished through: 1) Lectures by leading experts on the basic concepts of molecular biology and the most recent developments in the translation of these concepts to clinical research and practice as demonstrated in their own research and experimental design; 2) Small group laboratory sessions to demonstrate important experimental techniques utilized in basic molecular biology; 3) One-on-one discussion opportunities with world leaders in the field to provide participants with scientific and career development advice, as well as other informal mentorship; 4) A grant writing exercise to introduce applicants to grant writing and the review process; and 5) An online community of faculty and attendees, both past and present, using social networking tools to facilitate exchange of scientific information and career development advice. We will evaluate the success of the Workshop in achieving its stated goals, including the use of program evaluations, faculty reviews, and trainee input, and use this information to continually refine the Workshop.