Defining mechanisms of distinct tissue damage in different rheumatic syndromes

描述（由申请人提供）：该教师发展研究核心将招募朱利叶斯·伯恩鲍姆博士和阿米·沙阿博士作为约翰霍普金斯大学流变学系的助理教授。在约翰霍普金斯的风湿病学分部是一个高度合作的环境，在v\/hich的诊断，管理和自身免疫性风湿性疾病的机制，在学术上严格和多学科的方式接近。该部门高度投资于发展初级教师的职业生涯，并在过去6年中成功指导了10名助理教授的发展（其中9名获得了美国国立卫生研究院的K赠款）。该部门已经建立的结构和系统（包括风湿病研究核心中心的可用性，由NIH资助并由慈善基金补充的试点和可行性资助计划，矩阵指导结构，与教师设置明确的里程碑的季度会议，兴趣小组和疾病中心小组会议，每周概念会议和赠款审查会议）将最大限度地提高职业发展。Birnbaum博士和Shah博士被选中是基于他们杰出的才能，他们在奖学金结束时成功竞争同行评审资金，以及他们在风湿性疾病（心肌和神经表型）中桥接重要界面的能力和兴趣，其中相互作用的合作伙伴是强大的，已经到位，并且重要贡献，独立性和职业发展的潜力很高。为他们的职业发展和成功制定了明确的计划，并且对这些候选人有明确的机构承诺，在P30补助金终止后的2年内为成功提供必要的资源。

DESCRIPTION (provided by applicant): This Faculty Development Research Core will recruit Dr. Julius Birnbaum and Dr. Ami Shah to the tenure track faculty as Assistant Professors in the Division of Rheumatology at Johns Hopkins University. The Division of Rheumatology at Johns Hopkins is a highly collaborative environment in v\/hich the diagnosis, management and mechanisms of autoimmune rheumatic diseases are approached in an academically rigorous and multi-disciplinary way. The division is highly invested in developing the careers of junior faculty, and has successfully guided the development of 10 assistant professors over the past 6 years (with 9 being awarded K grants from the NIH). Structures and systems already established in the Division (including availability of a Rheumatic Disease Research Core Center, a pilot and feasibility grant program funded by the NIH and supplemented by philanthropic funds, a matrix mentoring structure, quarterly meetings with faculty setting explicit milestones, interest groups and Disease Center group meetings, weekly concept sessions, and grant review sessions) will maximize career growth. Drs. Birnbaum and Shah have been chosen based on their outstanding talents, their successful competition for peer-reviewed funding at the end of fellowship, and their ability and interest in bridging important interfaces in the rheumatic diseases (cardiac muscle and neurological phenotypes), where the interacting partners are strong and already in place, and the potential for an important contribution, independence and career growth is high. A clear plan for their career development and success is in place, and there is an explicit Institutional commitment to these candidates to provide the resources necessary for success for 2 years following the termination of this P30 grant.