Adminstrative Core

克拉克博士将在项目经理卡里·特雷维诺的协助下管理这一核心。这个核心将协调 这个项目项目的不同方面。以下是主要的行政职能。特雷维诺女士 负责项目的行政和拨款管理方面的工作。她会协调 会议，安排特定项目的旅行，跟踪支出，确保项目支出满足NIH的要求 政策规则，并正确分配，最后就监管事项向私人投资提供咨询和信息。每年一次 进度报告、财务摘要和最后文件的编写由 管理核心。 每个单独项目的PI和COPI将负责其提案中的具体目标。 简而言之，克拉克博士是项目1的PI和动物核心。他将负责分离实体肿瘤 癌症干细胞和异种移植模型。魏斯曼博士是项目2的负责人，将负责 用于分离血液干细胞。奎克博士是项目3的PI，将负责微流体 分析。他将进行单细胞阵列和微型组织培养分析。奥特曼博士将领导 生物信息学核心，并将分析地震实验室产生的数据。

Dr. Clarke will administer this core, assisted by Kari Trevino, Program Manager. This core will coordinate the different aspects of this program project. The following are the major administrative functions. Ms. Trevino is responsible for the administration and grants management aspects of the program. She will coordinate meetings, arrange for project-specific travel, track expenditures, assure that project expenditures meet NIH policy rules and are correctly allocated, and finally advise and inform the PI on regulatory matters. Annual progress reports and financial summaries and final document preparation are the responsibility of the Administrative Core. The Pi's and CoPIs of each individual project will be responsible for the specific aims in their proposals. Briefly, Dr. Clarke is PI of Project 1 and the animal core. He will be responsible for isolation of the solid tumor cancer stem cells and the xenograft models. Dr. Weissman is the leader of Project 2 and will be responsible for isolation of blood stem cells. Dr. Quake is PI of Project 3 and will be responsible for the microfluidic analyses. He will do the single cell arrays and the miniaturized tissue culture analyses. Dr. Altman will lead the bioinformatics core and will analyze the data generated by the Quake laboratory.