Core F: Canine Cell & Molecular Resources

核心F是一种正在开发的核心，旨在产生犬类特有的细胞和分子试剂 提高犬模型在新疗法临床前安全性和有效性测试中的价值。作为一名 狗是一种体型较大、寿命相对较长、繁育过度的物种，与人类有许多相似之处。特别是在以下方面 对于造血和干细胞移植，狗的模型已经高度预测了 人类患者，包括移植物抗宿主病的发展及其对治疗的反应。在……里面 添加到已有的细胞系、组织、DNA和cDNA上。核心F将产生犬类特有的shRNA 用于拆卸实验的库。

Core F is a developing core designed to generate canine specific cell and molecular reagents to enhance the value of the canine model for preclinical safety and efficacy testing of new therapeutics. As a large, relatively long-lived, out bred specie, the dog has many similarities with humans. Specifically in regard to hematopoiesis and stem cell transplantation the dog model has been highly predictive of outcomes in human patients, including the development of graft-versus-host disease and its response to treatment. In addition to celllines, tissue, DNA, and cDNA already available. Core F will generate canine specific shRNA libraries for knock down experiments.